Perelman School of Medicine

PHILADELPHIA — Periodontitis, a form of chronic gum disease that affects nearly half of the U.S. adult population, results when the bacterial community in the mouth becomes unbalanced, leading to inflammation and eventually bone loss. In its most severe form, which affects 8.5 percent of U.S. adults, periodontitis can impact systemic health.

Katherine Unger Baillie ・December 7, 2012

PHILADELPHIA — Transplant surgeons at the Perelman School of Medicine at the University of Pennsylvania have successfully used a new technique that repairs damaged donated lungs that would have been unusable, allowing for successful transplantation of the reconditioned lungs into a patient.

Jessica Mikulski ・December 6, 2012

PHILADELPHIA – New research from the Perelman School of Medicine at the University of Pennsylvania and the Philadelphia VA Medical Center indicates that the implementation of protected sleep periods for residents who are assigned to overnight shifts in a hospital represent a viable tool in preventing fatigue and alleviating the physiological and behavior

Jessica Mikulski ・December 4, 2012

PHILADELPHIA – Five faculty members at the University of Pennsylvania have been named Fellows of the American Association for the Advancement of Science.  Two are from Penn’s Perelman School of Medicine, two are from its School of Arts and Sciences

Karen Kreeger, Evan Lerner ・November 30, 2012

PHILADELPHIA — H. Lee Sweeney, Ph.D., the William Maul Measey Professor at the Perelman School of Medicine, University of Pennsylvania, has been named the inaugural director of Penn’s Center for Orphan Disease Research and Therapy.

Karen Kreeger ・November 29, 2012

PHILADELPHIA — Most healthy cells rely on a complicated process to produce the fuel ATP. Knowing how ATP is produced by the cell’s energy storehouse – the mitochondria -- is important for understanding a cell’s normal state, as well as what happens when things go wrong, for example in cancer, cardiovascular disease, neurodegeneration, and many rare disorders of the mitochondria.

Karen Kreeger ・November 26, 2012

PHILADELPHIA – Dorothy Roberts will deliver the keynote speech on “The Racial Geography of Child Welfare” at the Field Center for Children’s Policy, Practice & Research Winter 2012 Community Symposium at the University of Pennsylvan

Jill DiSanto ・November 26, 2012

PHILADELPHIA — A pathway called the “Unfolded Protein Response,” or UPR, a cell’s way of responding to unfolded and misfolded proteins, helps tumor cells escape programmed cell death during the development of lymphoma.

Karen Kreeger ・November 21, 2012

PHILADELPHIA — Several fatal brain disorders, including Parkinson's disease, are connected by the misfolding of specific proteins into disordered clumps and stable, insoluble fibrils called amyloid. Amyloid fibrils are hard to break up due to their stable, ordered structure. For example, a-synuclein forms amyloid fibrils that accumulate in Lewy Bodies in Parkinson's disease.

Karen Kreeger ・November 15, 2012

PHILADELPHIA — Just north of Philadelphia, the communities of West and South Ambler are working to recover from the ramifications of their town’s long-closed asbestos factory.

Katie Delach ・November 15, 2012