Perelman School of Medicine

The immune health future, today

Breaking the code of the immune system could provide a new fundamental way of understanding, treating, and preventing every type of disease. Penn Medicine is investing in key discoveries about immunity and immune system function, and building infrastructure, to make that bold idea a reality.

An unsolved mystery: Why are we sleepy when sick?

David Raizen, a professor of neurology, alongside PURM student Hina Sako, spent the summer moving forward research examining how sickness affects sleep.

Deans of health schools discuss climate change in their fields

Deans and leaders from the schools of Medicine, Veterinary Medicine, Dental Medicine, Nursing, and Social Policy & Practice discussed climate and health at a Climate Week event.

The brain-blood barrier’s role in governing ant behavior

New research from Penn Medicine uncovers a link between a single enzyme and complex social behaviors in ants.

Stroma-targeting CAR T cells (green) in the stroma surrounding a solid tumor.

Removing the barrier surrounding solid tumors clears path for T cells

Penn researchers uncover a new way to target solid tumors. Using CAR T cells to remove cancer-associated fibroblasts surrounding pancreatic tumors allows T cells to infiltrate and attack the tumor cells.

Penn Medicine’s Carl June to receive 2024 Breakthrough Prize in Life Sciences

The Richard W. Vague Professor in Immunotherapy in the Perelman School of Medicine is honored for pioneering the development of CAR T cell therapy, which programs patients’ own immune cells to fight their cancer.

A Perry World House forum at the University of Pennsylvania discusses how lessons from COVID-19 can impact the fight to end malaria

Can the COVID playbook help end malaria?

In a Perry World House conversation, Matthew Laurens, Martina Mchenga, and Drew Weissman discussed how lessons from a global pandemic could help in the fight to eradicate malaria.

Fluorescent microscopy of colon cancer cells..

Genetic switch turns tumor suppressor into oncogene in colorectal cancer

Researchers from the School of Veterinary Medicine have shown that an enzyme that suppresses early-stage colorectal cancer switches to become an oncogene as the cancer progresses.

rendering of a brain and its different sections highlighted as different colors.

A link between memory and appetite in the brain to explain obesity

Penn Medicine researchers have found the hippocampal subnetwork, located within the memory center of the brain, is more dysregulated in patients with higher body mass indexes, leading to an inability to control or regulate eating habits.

Microscopic rendering of a white blood cell amongst red blood cells.

An immunotherapy strategy against all blood cancers

Researchers at Penn Medicine have demonstrated a new potential treatment using CAR T cell therapy using a CRISPR base-editing to develop a method called “epitope editing.”

Filters