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High pregnancy weight gain tied to higher risk of death in the following decades
Pregnant person standing on a floor scale.

Image: iStock/Liudmila Chernetska

High pregnancy weight gain tied to higher risk of death in the following decades

Findings from a Penn Medicine study, which analyzed 50 years of data, highlights the health risks tied to conditions like heart disease and diabetes that can occur when more weight is gained in pregnancy than recommended.

Frank Otto

Leveraging the body’s postal system to understand and treat disease
Isolated microfluidic chip with blood sample inside of micropipette 3d rendered in the black background

A research team led by Jina Ko of the School of Engineering and Applied Science and Perelman School of Medicine has developed a new way to characterize the contents of a cargo-carrying particle excreted by many cells, extracellular vesicles.

(image: iStock / Love Employee)

Leveraging the body’s postal system to understand and treat disease

An interdisciplinary team of researchers in the School of Engineering and Applied Science, Perelman School of Medicine, and School of Arts & Sciences has developed a technique that allows for characterization of both individual carrier and cargo for clinically important molecules.
Study shows promise for iNKT cell platform to treat cancer
Canine iNKT cells.

Canine iNKT cells

(Image: Courtesy of Nicola Mason and Antonia Rotolo)

Study shows promise for iNKT cell platform to treat cancer

Researchers from the School of Veterinary Medicine and Perelman School of Medicine have shown that invariant natural killer T cells from a healthy donor can persist in MHC-mismatched canines, demonstrating a reliable platform to inform human clinical trials.
Measuring the ripple effects of reforestation and sustainable cocoa cultivation
cocoa beans

(Image: Christina Seybolt, courtesy of Heather Huntington)

Measuring the ripple effects of reforestation and sustainable cocoa cultivation

With support from the Penn Global Engagement Fund, Heather Huntington is investigating the impact of reforestation and sustainable agriculture interventions on livelihoods, biodiversity, and human health in Ghana and Côte d’Ivoire.

Liana F. Wait

Combined treatment takes a bite out of tooth decay
Visual illstration of a tooth being shielded from bateria.

Michel Koo of the School of Dental Medicine and David Cormode of the Perelman School of Medicine and the School of Engineering and Applied Science led a team of researchers that uncovered a way to combine two FDA-approved treatments to treat tooth decay that taps into the blend’s bacteria-killing capabilities without disrupting the mouth’s microbiome.

(Image: iStock / Alex Sholom)

Combined treatment takes a bite out of tooth decay

A collaborative interdisciplinary team of researchers from Penn Dental, Medicine and Penn Engineering have discovered a game-changing synergy between ferumoxytol and stannous fluoride in treating dental caries.
Disparities persist across levels of surgery department leadership in U.S.
Doctors and nurses performing surgery.

Image: sfam_photo for Shutterstock

Disparities persist across levels of surgery department leadership in U.S.

A new Penn Medicine-led study highlights the need for thoughtful leadership planning to increase representation of women and minorities in roles with paths for promotion.

From Penn Medicine News

Viral persistence and serotonin reduction can cause long COVID symptoms
A profile of a human brain covered in virus cells.

Image: iStock/Rasi Bhadramani

Viral persistence and serotonin reduction can cause long COVID symptoms

A new Penn Medicine study finds components of the SARS-CoV-2 virus remain in the gut of some long COVID patients, causing persistent inflammation, vagus nerve dysfunction, and neurological symptoms.

From Penn Medicine News

Neanderthals carried genes acquired from ancient interactions with ‘cousins’ of modern humans
Researchers collecting ethnographic and medical information from participants in Ethiopia.

Members of Tishkoff's research team collecting ethnograpgic information from participants in Ethiopia.

(Image: Courtesy of Sarah Tishkoff)

Neanderthals carried genes acquired from ancient interactions with ‘cousins’ of modern humans

A new collaborative study led by Sarah Tishkoff shows that Neanderthals inherited at least 6% of their genome from a now-extinct lineage of early modern humans.
Understanding the brain via a molecular map
Abstract polygonal brain with connected dots and lines. Artificial intelligence 3d illustration.

PIK Professor Michael Platt and collaborators have generated the first single-cell “atlas” of the primate brain to help explore links between molecules, cells, brain function, and disease.

(Image: iStock / Jezperklauzen)

Understanding the brain via a molecular map

PIK Professor Michael Platt and collaborators have generated the first single-cell “atlas” of the primate brain to help explore links between molecules, cells, brain function, and disease.