11/15
School of Dental Medicine
Drivers of inflammation provide valuable targets for new gum disease therapies
A subset of T cells contributes to the inflammation and bone loss that characterizes periodontitis, a severe form of gum disease. According to new research by George Hajishengallis and scientists at the National Institutes of Health, drugs that specifically inhibit these cells may offer an effective therapy.
Targeting a viral vulnerability to treat disease
Robert Ricciardi company ViRAZE utilizes interdisciplinary approaches to drug discovery. Its first target is molluscum contagiosum, a disease that targets children and immune-compromised adults with no current FDA-approved therapy.
Regrowing dental tissue with stem cells from baby teeth
In a clinical trial led by Songtao Shi of the School of Dental Medicine, stem cells extracted from baby teeth were used to regrow the living tissue in teeth damaged by injury. The promising findings highlight the potential of dental stem cells, which could be used in a wide range of dental procedures, or treating certain systemic diseases.
Mentoring program introduces high school students to dentistry
The Summer Mentorship Program introduces first-generation and under-represented high school students in Philadelphia to higher education possibilities, including Penn Dental School's four-week immersion program that includes hands-on experience and mentorship with current dental students.
Dental plaque is no match for catalytic nanoparticles
A recent study found that nanoparticles can break down dental plaque with nanoparticles that target biofilms, preventing tooth decay in humans and animal models without damaging surrounding oral tissue.
Ice cream conundrum
The refreshing delight of ice cream on a hot summer day has its dangers: tooth sensitivity and the familiar feeling of “brain freeze.” Scientists break down the causes of the discomfort we are so willing to endure.
Dental researchers identify protein key to wound healing
Resesarch from Penn Dental reveal that the cells that line the skin and mucosa play a role in blood-vessel formation through a protein called Foxo1, and targeting it may modulate the process of healing wounds.
Dental School’s Joan Gluch promotes academics and community engagement
A recipient of the third annual Netter Center Faculty-Community Partnership Award, Gluch and Philadelphia FIGHT will share award funding to develop projects to promote community oral health.
Promoting cross-campus collaborations in health research
The One Health Communications Group is a collaboration that brings together several schools and centers to develop groundbreaking health research in a cross-disciplinary and innovative environment.
Bacteria boost antifungal drug resistance in severe childhood tooth decay
Some young children experience severe tooth decay that resist normal therapies. New research led by Dongyeop Kim and Hyun (Michel) Koo of the School of Dental Medicine shows how plaque’s protective matrix can shield fungal cells from the drugs intended to kill them.
In the News
Does your jaw click? Do you grind your teeth? It could be this little-known condition
Thomas P. Sollecito of the School of Dental Medicine says that roughly 10-15% of adults have some form of temporomandibular disorder, though the vast majority don’t require treatment.
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Menopause can bring on dental problems, but you can protect your mouth
Thomas Sollecito of the School of Dental Medicine says hormonal changes can reduce bone density and saliva production, harming gums and teeth.
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Six health myths about oils
Dean Mark Wolff of the School of Dental Medicine says that oil pulling won’t cause harm but has never reversed periodontitis or gingivitis.
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Swish, spit, repeat: Is oil pulling good for your teeth?
Mark S. Wolff of the School of Dental Medicine says that oil pulling should never be a substitute for brushing or flossing one’s teeth.
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The five best water flossers (for people who hate flossing)
Dean Mark Wolff of the School of Dental Medicine explains which features are most helpful for a good water flosser.
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