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Blocking tumor signals can hinder cancer’s spread
Fluorescent microscopic image of lung tissue stained in blue and pink

Studying the molecular players that foster cancer’s spread, a team of basic science researchers from Penn have identified a way to halt it. By inhibiting an enzyme, they successfully reduced the spread of lung metastases in a mouse model of melanoma, also significantly prolonging survival. (Image: Courtesy of Serge Fuchs)

Blocking tumor signals can hinder cancer’s spread

A cross-campus team led by Serge Fuchs of the School of Veterinary Medicine used an inhibitor of an enzyme called p38α kinase to suppress the spread of melanoma to the lungs in a mouse model.

Katherine Unger Baillie

Side Gigs for Good during COVID-19
Person wearing a face mask in a grocery store standing next to a shopping cart.

Side Gigs for Good during COVID-19

Whether making masks, writing letters, raising funds, or shopping for neighbors, members of the Penn community have stepped up during the pandemic to support those in need.

Michele W. Berger, Katherine Unger Baillie

Coming together to solve the many scientific mysteries of COVID-19
Colorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (purple), isolated from a patient sample.

Colorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (purple), isolated from a patient sample. Image captured and color-enhanced at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. (Image: National Institute of Allergy and Infectious Diseases, NIH)

Coming together to solve the many scientific mysteries of COVID-19

Putting some of their regular research projects on the back burner, researchers around Penn are digging into unknowns about the novel coronavirus from their deep and varied perspectives.

Katherine Unger Baillie

Supporting agriculture and a safe food supply
cows in a field at new bolton center

In pre-Covid-19 times, the Marshak Dairy at Penn Vet’s New Bolton Center was a place for teaching as well as research. Now an essential crew of workers remain to care for the cows, as other veterinarians in the School continue to care for livestock around the region. (Credit: Penn Vet)

Supporting agriculture and a safe food supply

Essential workers in the School of Veterinary Medicine are caring for livestock, keeping track of disease, ensuring product consistency, and communicating with farmers to ensure that farms can continue providing a reliable food supply for the community.

Katherine Unger Baillie

Health care education in a virtual world
Screenshot of veterinary online course with picture of a cat

Health care education in a virtual world

For future health care providers, moving education online has proved especially challenging. With ingenuity and creativity, faculty are helping them continue gaining the skills they’ll need.

Katherine Unger Baillie

‘Disease knows no borders’
Lazaretto quarantine hospital

‘Disease knows no borders’

From the history of science to medical anthropology, governance, and economics, Penn experts look at the history of global health from different perspectives to see what the future may hold.

Kristina García

Penn labs get creative to stay productive, connected
thomas mallouk lab with researcher

Penn labs get creative to stay productive, connected

In the face of a pandemic that has shuttered most physical laboratories across campus, researchers have shifted gears, maintaining work and social ties through grant- and manuscript-writing, virtual journal clubs, online coffee breaks, and more.

Michele W. Berger

Tailoring treatment for triple-negative breast cancer
Fluorescent microscopic image shows mammary gland cells

Researchers from Penn Vet found that that the protein Elf5 in mammary tumors plays a role in the disease’s progression and spread. Cells with Elf5 are noted in green above. (Image: Snahlata Singh and Rumela Chakrabarti)

 

 

Tailoring treatment for triple-negative breast cancer

Research led by the School of Veterinary Medicine’s Rumela Chakrabarti identified a molecular pathway responsible for the disease’s progression and spread.

Katherine Unger Baillie

Researchers, schools answer the call for personal protective equipment and critical supplies
researchers in the singh nano labs

Postdoctoral researcher Sam Nicaise, center, working on newly-made nanocardboard plates. Bargatin and his team have spent years creating this and other ultralight materials, using the state-of-the-art nanofabrication and characterization equipment inside the Singh Center.

Researchers, schools answer the call for personal protective equipment and critical supplies

To help in the ongoing fight against the novel coronavirus, groups across campus are donating what they can, from masks and gloves to ventilators.

Erica K. Brockmeier