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  • Health Sciences
  • Navigating cytokine storms

    Pairing their expertise, Nilam Mangalmurti of the Perelman School of Medicine and Christopher Hunter of the School of Veterinary Medicine have been working to understand the protective and harmful aspects of the immune response, including in COVID-19.
    Illustration of a T cell releasing signaling molecules, IL-4, IL-5, IL-6, IL-10, and IL-13
    An immune response can be helpful, harmful, or somewhere in between, in COVID-19 and many other medical conditions. 

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  • Exposure to air pollution worsens Alzheimer’s disease
    Emissions from a power plant.

    Image: Pencho Chukov via Getty Images

    Exposure to air pollution worsens Alzheimer’s disease

    New research from Penn Medicine finds living in areas with high concentration of air pollution is associated with increased buildup of amyloid and tau proteins in the brains of Alzheimer’s patients, accelerating cognitive decline.

    Sep 9, 2025

    What stiffening lung tissue reveals about the earliest stages of fibrosis
    Donia Ahmed prepares tissue for imaging.

    Image: Courtesy of Penn Engineering Today

    What stiffening lung tissue reveals about the earliest stages of fibrosis

    A Penn Engineering team has targeted the lung’s extracellular matrix to better understand early fibrosis by triggering the formation of special chemical bonds that increase tissue stiffness in specific locations, mimicking the first physical changes that may lead to lung fibrosis.

    Sep 12, 2025