Bioengineering

A faster way to make drug microparticles

Penn Engineers have developed a liquid assembly line process that controls flow rates to produce particles of a consistent size at a thousand times the speed.

Evan Lerner

Calculus III for cells

Cells can sense and respond to surface curvature in very clever ways. The results, which revealed that curvature is a profound biological cue, could pave the way to new tools in the field.

Ali Sundermier

Researchers show that cells’ perception of stiffness is a matter of time

The relative stiffness of a cell’s environment is known to have a large effect on that cell’s behavior, including how well the cell can stick or move. Now, a new study by University of Pennsylvania researchers demonstrates the role timing plays in how cells perceive this stiffness.

Ali Sundermier Evan Lerner

The future of technology

As new technologies emerge, they bring with them new ethical challenges. The topic of the future of technology was front and center on day three of the Penn Teach-in.

Ali Sundermier

Penn engineers test drug transfer using placenta-on-a-chip

Researchers at the University of Pennsylvania’s School of Engineering and Applied Science have demonstrated the feasibility of their “organ-on-a-chip” platform in studying how drugs are transported across the human placental barrier.

Ali Sundermier, Evan Lerner

Penn chemists develop 'motion capture' technology for tracking protein shape

In many modern animated movies, the trick to achieving realistic movements for individual characters and objects lies in motion-capture technology. This process often involves someone wearing a tracking suit covered in small, colored balls while a camera captures the position of those colored balls, which is then used to represent how the person is moving.

Ali Sundermier



In the News


The New York Times

Can your personal medical devices be recycled?

A lab at the School of Engineering and Applied Science led the development of a COVID test made from bacterial cellulose, an organic compound.

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Science Alert

Scientists think they’re on the verge of breaching the blood-brain barrier

Michael Mitchell of the School of Engineering and Applied Science and colleagues have constructed a model that could potentially allow drug transporters to bypass the blood-brain barrier.

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Popular Mechanics

How severed cockroach legs could help us ‘fully rebuild’ human bodies

David Meaney of the School of Engineering and Applied Science oversees an undergraduate bioengineering lab that uses cockroach legs to teach students to work with human prostheses.

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United Press International

Herniated discs could be repaired with biologic patch one day, researchers say

Preclinical research by Robert Mauck of the Perelman School of Medicine, Thomas Schaer of the School of Veterinary Medicine, and Ana Peredo, a Ph.D. graduate of the School of Engineering and Applied Science, reveals how a biologic patch activated by natural motion could become a key tool for repairing herniated discs in the back and relieving pain.

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NPR

Thanks, Neanderthals: How our ancient relatives could help find new antibiotics

A study by César de la Fuente of the Perelman School of Medicine and colleagues used AI to recreate molecules from ancient humans that could be potential candidates for antimicrobial treatments.

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New York Post

Why CAR T cell therapy is the cancer killer the world needs now

Research from Michael Mitchell of the School of Engineering and Applied Science has developed a new method to stop cytokine release during CAR T cell therapy, preventing some of its more dangerous side effects.

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