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Bioengineering

A potential strategy to improve T cell therapy in solid tumors
Microscopic view of a DNA strand.

Image: Courtesy of Penn Medicine News

A potential strategy to improve T cell therapy in solid tumors

A new Penn Medicine preclinical study finds that a new simultaneous “knockout” of two inflammatory regulators boosted T cell expansion to attach solid tumors.

From Penn Medicine News

New insights into the mechanisms of tumor growth
3d render of cells secreting exosomes.

Nocred

New insights into the mechanisms of tumor growth

A team of researchers led by the School of Arts & Science’s Wei Guo characterize the molecular pathways that play a major role in tumorigenesis, findings that could lead to better diagnostic tools for cancer and new targeted therapies.
OCTOPUS, an optimized device for growing mini-organs in a dish
A gloved hand holding a square petri dish with twelve slots.

OCTOPUS, an optimized device for growing mini-organs in a dish

With OCTOPUS, Dan Huh’s team expands organoid research with a platform superior to conventional gel droplets, allowing researchers to replicate biological systems outside of the body.

From Penn Engineering Today