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Researchers measure different types of curiosity studying ‘hunters and busybodies’
Illustration of person on a computer with two information path bubbles coming out of the computer that describe The Hunter and The Busybody.

Curiosity styles as knowledge networks where each node is a Wikipedia page and the paths between nodes represent the similarity between pages. “The hunter” style is characterized by high clustering and low overall path length, while “the busybody” style is characterized by low clustering and high overall path length. (Image: Melissa Pappas)

Researchers measure different types of curiosity studying ‘hunters and busybodies’

A multidisciplinary study has found a way to readily quantify the information-seeking associated with curiosity and explore mechanisms underlying information-seeking.

From Penn Engineering Today

Ruby Washington is poised to make her mark in bioengineering
Ruby Washington holds a bioengineered cast in the shape of a human leg.

Ruby Washington is poised to make her mark in bioengineering

The senior in Penn Engineering’s Department of Bioengineering weds biomedicine and her pursuit in addressing healthcare disparities in the Black community.

From Penn Engineering Today

One step closer to an at-home, rapid COVID-19 test
A hand in a black rubber gloves holding a cell phone with a sensor attached. A dropper is touching the sensor.

Created in the lab of César de la Fuente, this miniaturized, portable version of rapid COVID-19 test, which is compatible with smart devices, can detect SARS-CoV-2 within four minutes with nearly 100% accuracy. (Image: Courtesy of César de la Fuente)

One step closer to an at-home, rapid COVID-19 test

The lab of César de la Fuente is working on a paper-based biosensor that could provide results in minutes. Clinical trials began Jan. 5.

Michele W. Berger

Using lung-on-a-chip technology to find treatments for chlorine gas exposure
Lung on a chip detail.

Huh’s organ-on-a-chip devices contain human cells, allowing for experiments that could not otherwise be practically or ethically performed. (Image: Penn Engineering Today)

Using lung-on-a-chip technology to find treatments for chlorine gas exposure

The new lung-on-a-chip platforms will help better understand how chlorine damages lung tissues and to discover specific biomarkers of chlorine gas-induced lung injury.

Evan Lerner

Nanoparticles can turn off genes in bone marrow
Microscopic view of lung cells expressing the synthetic mRNA

Nanoparticles delivering messenger RNA to specific organs. (Image: Penn Engineering Today)

Nanoparticles can turn off genes in bone marrow

Using specialized nanoparticles, researchers from Penn Engineering and MIT have developed a way to turn off specific genes in cells of bone marrow, which play an important role in producing blood cells. 

From Penn Engineering Today

Engineers coax white blood cells to crawl upstream
HL-60 cells treated with a Mac-1 blocking antibody migrate upstream on ICAM-1 at a shear rate of 800s-1

HL-60 cells treated with a Mac-1 blocking antibody migrate upstream on ICAM-1 at a shear rate of 800s-1. (Image: Penn Engineering)

Engineers coax white blood cells to crawl upstream

Penn engineers find that by fighting the direction of the blood flow, white blood cells forge a faster route to battle infections.

Penn Today Staff

Computer-generated antibiotics and biosensor Band-Aids
cesar de la fuente in his lab

Computer-generated antibiotics and biosensor Band-Aids

For Penn synthetic biologist César de la Fuente and his team, these concepts aren’t some far-off ideal. They’re projects already in progress, and they have huge real-world implications should they succeed.

Michele W. Berger

Strella Biotechnology tackles food waste by ‘hacking the fruit’
strella biotech team members working in the lab

Strella Biotechnology tackles food waste by ‘hacking the fruit’

President’s Innovation Prize awardees Katherine Sizov and Malika Shukurova are expanding their startup and confronting $1 trillion of food waste with their novel biosensing technology.

Erica K. Brockmeier