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Liquid crystals in motion mimic biological systems
Various undulating shapes of crystals.

Under the right conditions, liquid crystals form structures reminiscent of biological systems, shown in actual (left) and false color (right), with the filaments in light blue and the flattened discs in yellow.

(Image: Christopher Browne)

Liquid crystals in motion mimic biological systems

Researchers in the lab of Chinedum Osuji have discovered that under the right conditions, liquid crystals form structures reminiscent of biological systems that can transport material from one place to another, much like complex biological systems.

Ian Scheffler

Uncovering new antibiotics inside the human gut
Microscopic rendering of bacterial in the small intestines.

Image: iStock/ChrisChrisW

Uncovering new antibiotics inside the human gut

Researchers from Penn Engineering, led by César de la Fuente, have leveraged AI to discover dozens of potential new antibiotics in the human gut microbiome.

Ian Scheffler

Building solutions for brain disorders
Flavia Vitale holding a vial with a gloved hand.

Flavia Vitale is an associate professor in bioengineering in Penn Engineering and in neurology in Penn Medicine.

(Image: Melissa Pappas)

Building solutions for brain disorders

Penn Engineering’s Flavia Vitale’s work developing devices that help people living with brain disorders has earned her a CAREER award, which will support her lab’s research in materials and devices that interface with different chemical and electrical signals inside the brain.

Melissa Pappas

Shedding light on cellular metabolism to fight disease
Yihui Shen.

Yihui Shen is the J. Peter and Geri Skirkanich Assistant Professor of Innovation in Bioengineering in the School of Engineering and Applied Science.

(Image: Courtesy of Penn Engineering Today)

Shedding light on cellular metabolism to fight disease

In Yihui Shen’s lab, the assistant professor of innovation in bioengineering, aims to advance the understanding of metabolism and open doors to new cancer treatments and therapies.

From Penn Engineering Today

Penn pioneers a ‘one-pot platform’ to promptly produce mRNA delivery particles
3D illustration showing cross-section of the lipid nanoparticle carrying mRNA of the virus entering a human cell.

Lipid nanoparticles present one of the most advanced drug delivery platforms to shuttle promising therapeutics such as mRNA but are limited by the time it takes to synthesize cationic lipids, a key component. Now, Michael Mitchell and his team at the School of Engineering and Applied Science have developed a faster way to make cationic lipids that are also more versatile, able to carry different kinds of treatments to target specific organs.

(Image: iStock / Dr_Microbe)

Penn pioneers a ‘one-pot platform’ to promptly produce mRNA delivery particles

New lipid platform enables rapid synthesis of molecules that can shuttle therapeutics for a range of diseases with a high degree of organ specificity.
Penn Engineering’s Ottman Tertuliano receives a 2024 CAREER Award
Ottman Tertuliano.

Image: Courtesy of Penn Engineering

Penn Engineering’s Ottman Tertuliano receives a 2024 CAREER Award

Tertuliano’s research on bone fractures at the nanoscale allows for research on two separate time scales: the forming of cracks in a fracture at 1 micrometer/second, and the cellular response and repair time scale, a much lengthier process.

From Penn Engineering Today