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Shedding light on cellular metabolism to fight disease
Technology.org

Shedding light on cellular metabolism to fight disease

Yihui Shen of the School of Engineering and Applied Science talks about her newly established lab where she aims to advance the molecular precision of coherent Raman imaging to allow researchers to understand the minutia of metabolism and open doors to new cancer treatments and therapies.

Shedding light on cellular metabolism to fight disease
Yihui Shen.

Yihui Shen is the J. Peter and Geri Skirkanich Assistant Professor of Innovation in Bioengineering in the School of Engineering and Applied Science.

(Image: Courtesy of Penn Engineering Today)

Shedding light on cellular metabolism to fight disease

In Yihui Shen’s lab, the assistant professor of innovation in bioengineering, aims to advance the understanding of metabolism and open doors to new cancer treatments and therapies.

From Penn Engineering Today

Penn pioneers a ‘one-pot platform’ to promptly produce mRNA delivery particles
3D illustration showing cross-section of the lipid nanoparticle carrying mRNA of the virus entering a human cell.

Lipid nanoparticles present one of the most advanced drug delivery platforms to shuttle promising therapeutics such as mRNA but are limited by the time it takes to synthesize cationic lipids, a key component. Now, Michael Mitchell and his team at the School of Engineering and Applied Science have developed a faster way to make cationic lipids that are also more versatile, able to carry different kinds of treatments to target specific organs.

(Image: iStock / Dr_Microbe)

Penn pioneers a ‘one-pot platform’ to promptly produce mRNA delivery particles

New lipid platform enables rapid synthesis of molecules that can shuttle therapeutics for a range of diseases with a high degree of organ specificity.
Penn Engineering’s Ottman Tertuliano receives a 2024 CAREER Award
Ottman Tertuliano.

Image: Courtesy of Penn Engineering

Penn Engineering’s Ottman Tertuliano receives a 2024 CAREER Award

Tertuliano’s research on bone fractures at the nanoscale allows for research on two separate time scales: the forming of cracks in a fracture at 1 micrometer/second, and the cellular response and repair time scale, a much lengthier process.

From Penn Engineering Today

Penn third-year named 2024 Udall Scholar
Joey Wu standing outside wearing a suit and tie

Third-year undergraduate Joey Wu has been named a 2024 Udall Scholar.

(Image: Courtesy of the Center for Undergraduate Research and Fellowships)

Penn third-year named 2024 Udall Scholar

Third-year Joey Wu, studying bioengineering and environmental science in the Vagelos Integrated Program in Energy Research (VIPER) program, has been named a 2024 Udall Scholar.
A novel technique to form human artificial chromosomes
Microscopic view of DNA.

Image: iStock/Mohammed Haneefa Nizamudeen

A novel technique to form human artificial chromosomes

Penn researchers say the new technique for making human artificial chromosomes from single, long constructs of designer DNA will allow for more efficient laboratory research.

Alex Gardner

Sherry Gao pushes the boundaries of genetic engineering
Sherry Gao.

Sherry (Xue) Gao, Presidental Penn Compact Associate Professor in Bioengineering.

(Image: Courtesy of Penn Engineering Today)

Sherry Gao pushes the boundaries of genetic engineering

The Presidential Penn Compact Associate Professor in Chemical and Biomolecular Engineering aims to make gene editing tools like CRISPR more accurate, and encourage first generation students along the way.

From Penn Engineering Today

New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control
Microscopic view of lipid nanoparticles.

Like space shuttles using booster rockets to breach the atmosphere, lipid nanoparticles equipped with the new molecule more successfully deliver medicinal payloads.

(Image: Courtesy of Penn Engineering)

New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control

Penn Engineering researchers have invented a new way to synthesize the key chemical components of lipid nanoparticles that help protect and deliver medicinal payloads.

From Penn Engineering Today