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Bioengineering

Refining lipid nanoparticles for better mRNA therapies
Microscopic rendering of mRNA inside a lipid nanoparticle.

Image: iStock/Love Employee

Refining lipid nanoparticles for better mRNA therapies

A new method developed by Penn engineers for designing ionizable lipids is expected to have broad implications for mRNA-based vaccines and therapeutics.

Ian Scheffler

Penn fourth-year Om Gandhi is a 2025 Rhodes Scholar
Om Gandhi.

Penn fourth-year Om Gandhi has been awarded a 2025 Rhodes Scholarship. 

(Image: Courtesy of Om Gandhi)

Penn fourth-year Om Gandhi is a 2025 Rhodes Scholar

Penn fourth-year Om Gandhi, from Barrington, Illinois, has been awarded a 2025 Rhodes Scholarship, which funds tuition and a living stipend for graduate study at the University of Oxford in England. He is among 32 American Rhodes Scholars, and an expected 100 worldwide.
Developing kidneys from scratch
Rendering of kidneys.

Image: iStock/Vladyslav Severyn

Developing kidneys from scratch

Bioengineering professor Alex Hughes tackles the burden of chronic kidney disease by creating kidney tissue from scratch, which could reduce the need for both dialysis and transplantation.

Ian Scheffler

New class of encrypted peptides offer hope in fight against antibiotic resistance
Microscopic view of a string of amino acids.

Image: iStock/Christoph Burgstedt

New class of encrypted peptides offer hope in fight against antibiotic resistance

New research by César de la Fuente finds that nearly 90% of peptides discovered exhibit significant antimicrobial properties, particularly through the disruption of bacterial membranes.

From Penn Medicine News

Penn’s Gilliam Fellows bridge inclusion and innovation
Brianna Hill-Payne and Sam Preza.

Penn’s Gilliam Fellows Brianna Hill-Payne (left) and Sam Preza.

(Image: Courtesy of Penn Medicine News)

Penn’s Gilliam Fellows bridge inclusion and innovation

Two Ph.D. students are among 50 graduate students selected to receive this year’s Howard Hughes Medical Institute Gilliam Fellowship, which advances equity and inclusion in science through a mentorship skills development course.

From Penn Medicine News

Liquid crystals in motion mimic biological systems
Various undulating shapes of crystals.

Under the right conditions, liquid crystals form structures reminiscent of biological systems, shown in actual (left) and false color (right), with the filaments in light blue and the flattened discs in yellow.

(Image: Christopher Browne)

Liquid crystals in motion mimic biological systems

Researchers in the lab of Chinedum Osuji have discovered that under the right conditions, liquid crystals form structures reminiscent of biological systems that can transport material from one place to another, much like complex biological systems.

Ian Scheffler