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Biology

Artificial chromosomes for disease modeling
The Scientist

Artificial chromosomes for disease modeling

A study by Ben Black of the Perelman School of Medicine and colleagues used a new technique for synthesizing chromosomes to introduce panels of genes into disease models, facilitating drug testing.

AI used to predict potential new antibiotics in groundbreaking study
The Guardian

AI used to predict potential new antibiotics in groundbreaking study

A study by César de la Fuente of the School of Engineering and Applied Science and Perelman School of Medicine used machine learning to predict potential new antibiotics in the global microbiome.

How deadly parasites choose to be male
Transcription atlas of Cryptosporidium life cycle.

Penn Vet researchers developed the Cryptosporidium single-cell atlas, revealing which genes are expressed at which points across the parasite’s life cycle. On the left, the atlas shows parasites replicating asexually in green, with males in blue and females in pink. On the right, micrographs of the stages are shown, with their nuclei highlighted in green.

(Image: Boris Striepen)

How deadly parasites choose to be male

Penn Vet researchers reveal the gene expression across the life cycle of Cryptosporidium and identify the determinant of maleness.
Penn Medicine creates human bird flu vaccine
6ABC.com

Penn Medicine creates human bird flu vaccine

Researchers at Penn Medicine have created a human bird flu vaccine using mRNA, the same platform as the COVID-19 vaccine.

How much gossip is needed to foster social cooperation?
One person whispers in the ear of another.

(Image: iStock/AndreyPopov)

How much gossip is needed to foster social cooperation?

Researchers Mari Kawakatsu, Taylor A. Kessinger, and Joshua B. Plotkin in Penn’s Department of Biology developed a model incorporating two forms of gossip to study indirect reciprocity.
A deep dive with Anna Kalandadze
Wearing her swim cap and goggles, Anna Kalandadze sits in the pool with her head above water.

Image: Eric Sucar

A deep dive with Anna Kalandadze

The fourth-year distance swimmer discusses swimming 11,000 yards a day, competing at the NCAA Championships, learning to dive from watching Michael Phelps, her interest in coral reef restoration, and getting circled by a shark.