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Penn pioneers a ‘one-pot platform’ to promptly produce mRNA delivery particles
3D illustration showing cross-section of the lipid nanoparticle carrying mRNA of the virus entering a human cell.

Lipid nanoparticles present one of the most advanced drug delivery platforms to shuttle promising therapeutics such as mRNA but are limited by the time it takes to synthesize cationic lipids, a key component. Now, Michael Mitchell and his team at the School of Engineering and Applied Science have developed a faster way to make cationic lipids that are also more versatile, able to carry different kinds of treatments to target specific organs.

(Image: iStock / Dr_Microbe)

Penn pioneers a ‘one-pot platform’ to promptly produce mRNA delivery particles

New lipid platform enables rapid synthesis of molecules that can shuttle therapeutics for a range of diseases with a high degree of organ specificity.
Takeaways from the U.K. elections
Keir Starmer shakes hands with supporters holding signs that say Change and look like the UK flag.

Labour Party leader Keir Starmer with his supporters at the Tate Modern in London on July 5, 2024.

(Image: AP Photo/Kin Cheung)

  • Q&A

    • Takeaways from the U.K. elections

    Political scientist Brendan O’Leary of the School of Arts & Sciences offers his take on the Labour Party’s landslide victory and what it means going forward.

    Kristen de Groot

    How to learn about a world-class double bass? Give it a CT
    Philadelphia Orchestra bassist Duane Rosengard; Peter Noël, director of CT Research at the Perelman School of Medicine; luthier Zachary S. Martin; Leening Liu, a Ph.D. student in Noël’s Laboratory of Advanced Computed Tomography Imaging; and Mark Kindig.

    Image: Courtesy of Penn Medicine News

    How to learn about a world-class double bass? Give it a CT

    Radiology experts at Penn Medicine applied imaging technology to centuries-old instruments to better understand how to care for masterworks built between the 17th and 19th centuries, and provide insights into building new ones.

    From Penn Medicine News