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New ways to modulate cell activity remotely
3D rendering of cells on a blue backdrop

Cells are dynamic, fast-changing, complex, tiny, and often hard-to-see in environments that don’t always behave in predictable ways when exposed to external stimuli. Now, researchers led by Lukasz Bugaj of the School of Engineering and Applied Science have found new ways to modulate cell activity remotely.

(Image: iStock/Maksim Tkachenko)

New ways to modulate cell activity remotely

Penn researchers use temperature to guide cellular behavior, promising better diagnostics and targeted therapies.
New quantum sensing technology reveals subatomic signals
The minute nucleic differences detectable using the form of nuclear quadrupolar resonance.

A rendering of the minute nucleic differences detectable using the form of nuclear quadrupolar resonance.

(Image: Mathieu Ouellet)

New quantum sensing technology reveals subatomic signals

Penn Engineers have created a novel approach to detect tiny variations in individual atoms, enabling protein research in drug development.

Ian Scheffler

How will the workplace change in 2025?
A bustling office space.

Image: iStock/piranka

How will the workplace change in 2025?

The Wharton School’s Peter Cappelli expects incremental changes in the workplace this year, a continuation of bigger trends that began during the pandemic.

From Knowledge at Wharton

Study shows drop in life expectancy in the Gaza Strip
Displaced Palestinians outside their tents near the seaside in Deir al-Balah in the central Gaza Strip.

Displaced Palestinians outside their tents near the seaside in Deir al-Balah in the central Gaza Strip in January 2025, following a ceasefire between Israel and Hamas.

(Image: Majdi Fathi/NurPhoto via AP)

Study shows drop in life expectancy in the Gaza Strip

A collaborative team of international researchers estimate that between Oct. 2023 and Sep. 2024 compared to pre-war levels, life expectancy in the Gaza Strip almost halved.
Breakthroughs in gene editing and expression control with mvGPT
Tyler Daniel using a pipette in a bioengineering lab.

Sherry Gao, Tyler Daniel (pictured), and their coauthors have developed a new tool that can simultaneously and independently edit multiple genes and regulate their expression.

(Image: Bella Ciervo)

Breakthroughs in gene editing and expression control with mvGPT

Penn Engineers have created a gene editing tool that can address different genetic diseases in the same cell.

Ian Scheffler

The motor driving Penn’s biomedical research
Michael Ostap

Michael Ostap is the interim senior vice dean and chief scientific officer of the Perelman School of Medicine.

(Image: Courtesy of Penn Medicine Magazine)

The motor driving Penn’s biomedical research

For nearly three decades, interim senior vice dean and chief scientific officer of the Perelman School of Medicine Michael Ostap has investigated how molecules such as myosin feel force, in an effort to understand how cellular mutations cause disease.

Meredith Lidard Kleeman for Penn Medicine Magazine

Nelson Flores looks back on decades of bilingual education
Two middle school students in a classroom.

Image: iStock/diego_cervo

Nelson Flores looks back on decades of bilingual education

Flores, a professor in Penn’s Graduate School of Education, uncovers why Latinx students have tested as underperforming in academic language for decades due to education policy and societal constraints.

From Penn GSE

A less clumpy, more complex universe?
Dark energy telescope with star trails

A less clumpy, more complex universe?

Researchers combined cosmological data from two major surveys of the universe’s evolutionary history and found that it may have become “messier and complicated” than expected in recent years.
The social structures that shape AI
A person using AI on computer keyboard.

Image: iStock/Userba011d64_201

The social structures that shape AI

There’s more hype than ever around artificial intelligence, but Assistant Professor of Sociology Benjamin Shestakofsky says it’s important to fully examine how the new technology fits into broader society.

Marilyn Perkins

Why the most successful companies are scalable

Why the most successful companies are scalable

Giant companies stay on top because they’re both more productive and scalable than their competitors, according to research from Wharton and the School of Arts & Sciences.

From Knowledge at Wharton

2 min. read