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Genomics

Novel coupled nanopore platform offers greater precision for detecting molecules
Artist depiction of DNA moving through a nanopore system.

Marija Drndić of the School of Arts & Sciences and Dimitri Monos of the Perelman School of Medicine and Children’s Hospital of Philadelphia led a team of researchers who developed a new nanostructure platform that allows for more precise detection and control of biomolecules, such as DNA and proteins. This exciting new platform signals a new era of synthetic biology, paving the way for enhanced DNA sequencing and protein conformation detection.

(Image: Courtesy of artist) 

Novel coupled nanopore platform offers greater precision for detecting molecules

An interdisciplinary team of researchers from Penn have created the first ever reusable coupled nanopore platform for detecting and guiding molecules, findings could pave the way for much improved DNA sequencing and molecule identification.
Understanding the brain via a molecular map
Abstract polygonal brain with connected dots and lines. Artificial intelligence 3d illustration.

PIK Professor Michael Platt and collaborators have generated the first single-cell “atlas” of the primate brain to help explore links between molecules, cells, brain function, and disease.

(Image: iStock / Jezperklauzen)

Understanding the brain via a molecular map

PIK Professor Michael Platt and collaborators have generated the first single-cell “atlas” of the primate brain to help explore links between molecules, cells, brain function, and disease.
See how stress affects inflammatory bowel disease
Scientific American

See how stress affects inflammatory bowel disease

A study by Christoph A. Thaiss of the Perelman School of Medicine and colleagues has traced two detailed molecular pathways from the brain to the gut that produce inflammatory bowel disease flare-ups.

How our genes make us prone to allergies
Indo-Asian News Service

How our genes make us prone to allergies

A team of researchers from the Perelman School of Medicine found that small changes in the protein called ETS1 can lead to an increased likelihood of allergic reactions that cause inflammation.

We may finally know why psychological stress worsens gut inflammation
New Scientist

We may finally know why psychological stress worsens gut inflammation

A study by Christoph Thaiss of the Perelman School of Medicine and colleagues identified a pathway between the brain and immune system in mice that may explain why psychological stress can worsen gut inflammation.