The mystery behind cleft palate and lips

New research identifies 100 new risk genes that could lead to the development of cleft lip and palate, combining molecular findings with genome data to find that many of the genes that are highly associated with clefting are located near the enhancer regions that work with a specific protein.

Penn Today Staff

In the News

Scientific American

See how stress affects inflammatory bowel disease

A study by Christoph A. Thaiss of the Perelman School of Medicine and colleagues has traced two detailed molecular pathways from the brain to the gut that produce inflammatory bowel disease flare-ups.


Smithsonian Magazine

Famed 5,300-year-old Alps Iceman was a balding middle-aged man with dark skin and eyes

Iain Mathieson of the Perelman School of Medicine says that the Iceman genome was one of the first ancient human genomes ever published.


Indo-Asian News Service

How our genes make us prone to allergies

A team of researchers from the Perelman School of Medicine found that small changes in the protein called ETS1 can lead to an increased likelihood of allergic reactions that cause inflammation.



House GOP inquiry over gain-of-function research targets a scientific giant

Stuart Isaacs of the Perelman School of Medicine speaks positively about his time studying poxviruses in Bernard Moss’ lab.



His baby gene editing shocked ethicists. Now he’s in the lab again

Kiran Musunuru of the Perelman School of Medicine says that Chinese geneticist He Jiankui crossed ethical lines and exhibited bad science by editing babies’ genes.


New Scientist

We may finally know why psychological stress worsens gut inflammation

A study by Christoph Thaiss of the Perelman School of Medicine and colleagues identified a pathway between the brain and immune system in mice that may explain why psychological stress can worsen gut inflammation.