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Immunology

The path from innovation to implementation
Tray of vials in a medical lab.

Image: Courtesy of Penn Medicine Magazine

The path from innovation to implementation

Penn’s infrastructure in both supporting clinical research and forging commercial partnerships smooths the way from idea to approval.

Karen L. Brooks for Penn Medicine Magazine

Two Penn faculty elected to the American Philosophical Society
Paul Offit and Dorothy Roberts.

Paul Offit, the Maurice R. Hilleman Chair of Vaccinology in the Department of Pediatrics at the Perelman School of Medicine, and director of the Vaccine Education Center at the Children’s Hospital of Philadelphia; and Dorothy E. Roberts, the George A. Weiss University Professor of Law and Sociology and the Raymond Pace and Sadie Tanner Mossell Alexander Professor of Civil Rights.

(Images: (Left) Courtesy of the Children’s Hospital of Philadelphia and (right) Sameer A. Khan)

Two Penn faculty elected to the American Philosophical Society

Paul Offit and Dorothy Roberts have been recognized for extraordinary accomplishments in their fields.
Improved gene editing method could power future cell and gene therapies
Microscopic view of DNA strands.

Image: Courtesy of Penn Medicine News

Improved gene editing method could power future cell and gene therapies

A new technique based on special cell-penetrating peptides promises advantages over current methods for editing the genomes of primary cells, such as patients’ T cells.

Why Penn research powers many FDA-approved treatments
Aerial image of Penn Medicine staff in the atrium celebrating.

On August 30, 2017, faculty and staff at the Perelman Center for Advanced Medicine gathered for a “flash mob” celebration of the the FDA approval of a Penn Medicine-developed personalized cellular immune therapy.

(Image: Courtesy of Penn Medicine News)

Why Penn research powers many FDA-approved treatments

Since 2017, the FDA approved more than two dozen new therapies with roots at Penn Medicine—almost half of which are first-in-class for their indications.

Karen L. Brooks for Penn Medicine Magazine

Moderna, Merck show progress toward cancer vaccines
The Wall Street Journal

Moderna, Merck show progress toward cancer vaccines

Robert Vonderheide of the Perelman School of Medicine says that a combined immunotherapy-vaccine approach could be a game changer for melanoma patients.

Novel treatment shows promise against rare cancer in kids
Associated Press

Novel treatment shows promise against rare cancer in kids

Carl June of the Perelman School of Medicine comments on the success of a new study using CAR-T cell therapy to combat tumors in children with a rare kind of cancer.

Could the silver lining of the pandemic be pan-vaccines?
The Hill

Could the silver lining of the pandemic be pan-vaccines?

Scott Hensley of the Perelman School of Medicine and colleagues have developed a vaccine that could provide a baseline level of protection against all 20 known flu strains.

A potential strategy to improve T cell therapy in solid tumors
Microscopic view of a DNA strand.

Image: Courtesy of Penn Medicine News

A potential strategy to improve T cell therapy in solid tumors

A new Penn Medicine preclinical study finds that a new simultaneous “knockout” of two inflammatory regulators boosted T cell expansion to attach solid tumors.

From Penn Medicine News