11/15
Internal Medicine
New study illuminates the biology of common heart disorder
New study illuminates the biology of common heart disorder
Dilated cardiomyopathy, an often fatal heart disorder, due to titin gene mutations involves both a shortage of good titin and a buildup of mutant, potentially “bad” titin.
A ‘dented’ internal clock informs shift workers’ weight gain and diabetes
A ‘dented’ internal clock informs shift workers’ weight gain and diabetes
Weight gain and high blood sugar caused by a damaged internal clock was corrected by Penn researchers, who changed the length of the day in tests.
Red blood cells play much larger role in immune system via DNA-binding
Red blood cells play much larger role in immune system via DNA-binding
Penn Medicine researchers have uncovered mechanism of how red blood cells detect and bind DNA, opening a new area of research for treatment of inflammatory diseases.
General anesthesia just as safe as spinal anesthesia after broken hip surgery
General anesthesia just as safe as spinal anesthesia after broken hip surgery
Challenging common beliefs, Penn research shows patterns of recovery to be similar for patients who received spinal anesthesia and those who got general anesthesia.
Geographic disparities in lower extremity amputation rates
Geographic disparities in lower extremity amputation rates
A new study published in the Journal of the American Heart Association shows that peripheral artery disease affects Black people and those of low socioeconomic status, and the U.S. health system is missing opportunities to slow or stop the progression.
National task force recommends removing race from kidney function equation
National task force recommends removing race from kidney function equation
Backed by Penn Medicine research, the new clinical recommendations will promote health equity and increase Black patients’ access to transplantation.
Imaging technology maps cells tied to inflammatory bowel disease
Imaging technology maps cells tied to inflammatory bowel disease
“Imaging mass cytometry” shows how cells tied to inflammatory bowel disease affect intestinal tissue, generating new theories for the progression of Crohn’s disease and ulcerative colitis.
The best new implants may be a piece of you
The best new implants may be a piece of you
Innovative techniques like autologous surgery involves implanting patients with something taken from a different part of their body, which eliminates the risk of infection and erosion of synthetic materials.
Minimizing disruption, maximizing sleep in the hospital
Minimizing disruption, maximizing sleep in the hospital
The Pavilion at the Hospital of the University of Pennsylvania has embraced the challenge of design for minimizing sleep disruption in hospitals.
Cytokine treatment promotes weight loss by ‘sweating’ fat
Cytokine treatment promotes weight loss by ‘sweating’ fat
A seemingly unremarkable observation—greasy hair—showed Penn researchers how the immune system could be targeted to reverse obesity.
In the News
Fox 29 (Philadelphia)
Shoppers react after 10 million pounds of meat recalled due to listeria contamination
Michael Cirigliano of the Perelman School of Medicine says that people who ate recalled chicken within the last day should be watched to ensure they aren’t developing fever, diarrhea, or nausea.
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KFF Health News
Patients are relying on Lyft, Uber to travel far distances to medical care
According to Krisda Chaiyachati of the Perelman School of Medicine, some insurance companies and cancer treatment centers pay for ride-hailing services to reduce missed medical appointments.
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Philadelphia Inquirer
Fox 29 anchor Mike Jerrick diagnosed with prostate cancer, recovering from surgery
Michael Cirigliano of the Perelman School of Medicine made the initial diagnosis of prostate cancer for veteran newscaster Mike Jerrick.
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Fox 29 (Philadelphia)
Philadelphia heat: Tips to avoid heat-related illness as dangerous heat lingers
Michael Cirigliano of the Perelman School of Medicine says that heat stroke, which can be fatal, starts as heat exhaustion then leads to more symptoms as the temperature rises.
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Time
What competitive eating does to the body
David Metz of the Perelman School of Medicine explains some of the effects of speed-eating.
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Stat
As a primary care physician, here’s how I hope to partner with AI
In an opinion essay, Jeffrey Millstein of the Perelman School of Medicine says that patients and clinicians should be active participants when incorporating AI into primary care.
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