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Armored CAR T cells break through immune suppression in solid tumors
The Scientist

Armored CAR T cells break through immune suppression in solid tumors

A study by Joseph Fraietta of the Perelman School of Medicine and colleagues found a way to “armor” CAR T cells, enabling them to get past immunosuppressors in prostate cancer.

New treatment target could counter bone loss
SciTechDaily

New treatment target could counter bone loss

A study from Shuying (Sheri) Yang of the School of Dental Medicine and colleagues identified a protein that regulates osteoclasts, the cells that break down bone, which may pave the way for new treatments that prevent bone loss.

A physician compelled to help Ukrainian refugees from thousands of miles away
A roadside aid site at a Ukrainian border.

Roadside aid site at the Ukrainian border. (Image: Penn Medicine News)

A physician compelled to help Ukrainian refugees from thousands of miles away

Chester County Hospital’s Kevin Sowti has assisted in humanitarian efforts globally. As an immigrant, he was compelled to help Ukrainian refugees fleeing Russia’s invasion.

From Penn Medicine News

Monkeypox: What is known and unknown
People lined up near a sign that says NJCRI Monkeypox Vaccine Clinic

At a monkeypox vaccine clinic in Newark, New Jersey, in mid-August, people line up to receive a dose of the Jynneos vaccine. Monkeypox case counts have jumped significantly since the beginning of summer. (Image: AP Photo/Seth Wenig)

Monkeypox: What is known and unknown

The current outbreak of monkeypox is showing no sign of slowing. Stuart Isaacs of the Perelman School of Medicine, an expert on poxviruses, sheds light on the disease, its prevention and treatment, and what to watch for this fall.

Katherine Unger Baillie

Cooler temps and northern climes associated with increased diabetes diagnoses in dogs
A reclining dalmatian dog is examined by a provider with a stethoscope

A team from Penn Vet has identified an association between colder weather and climates and diabetes diagnoses in dogs. A parallel link is seen in diagnoses of Type 1 diabetes in people. 

Cooler temps and northern climes associated with increased diabetes diagnoses in dogs

Mirroring a finding in humans, diabetes diagnoses in dogs were more common in colder areas of the U.S. and during winter, according to a new study led by School of Veterinary Medicine researchers.

Katherine Unger Baillie

A novel method for monitoring the ‘engine’ of pregnancy
fetus in the uterus showing connection to placenta

A novel method for monitoring the ‘engine’ of pregnancy

By combining optical measurements with ultrasound, researchers were able to study oxygen levels in the placenta, paving the way for a better understanding of this complex, crucial organ.

Erica K. Brockmeier, Katherine Unger Baillie

Personalized immunotherapy shows promise beyond cancer
ScienceFriday.com

Personalized immunotherapy shows promise beyond cancer

Carl June of the Perelman School of Medicine is interviewed on the use of customized immunotherapy to treat new blood cancers, as well as its potential for treating solid state cancers and autoimmune diseases.

Penn Medicine’s 1,500th lung transplant
Garcia Bolton.

Garcia Bolton, a lifelong Philadelphian, received Penn Medicine’s 1500th lung transplant. (Image: Penn Medicine News)

Penn Medicine’s 1,500th lung transplant

The milestone transplant helped give new life to Garcia Bolton, a father, truck driver, poet, and lifelong Philadelphian.

Alex Gardner

Police officer dies after medical emergency in Louisiana heat
The New York Times

Police officer dies after medical emergency in Louisiana heat

Sameed Khatana of the Perelman School of Medicine comments on the number of deaths due to heat-related illnesses that could be underreported because many death certificates do not list heat as a cause of death.