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New Penn Vet study uncovers a key guardian of gut health and metabolism
Oriol Sunyer pointing to rainbow trout, the fish species used for the reported study.

Oriol Sunyer points out rainbow trout, the fish species used for the reported study.

(Image: Courtesy of Penn Vet)

New Penn Vet study uncovers a key guardian of gut health and metabolism

Researchers at the School of Veterinary Medicine unveil the critical role of secretory immunoglobulin M (sIgM) in maintaining microbiota balance, regulating metabolism, and protecting against disease.

Martin Hackett

2 min. read

‘Leukemia-on-a-chip’ could transform CAR T blood cancer treatments
The actual chip of human leukemia bone marrow where chambers and channels were filled with food dyes.

The actual chip of human leukemia bone marrow where chambers and channels were filled with food dyes.

(Image: NYU Tandon Applied Micro-Bioengineering Laboratory/Courtesy of Weiqiang Chen)

‘Leukemia-on-a-chip’ could transform CAR T blood cancer treatments

In a collaborative effort with NYU, Penn researchers have helped pioneer a novel 3D platform that mimics the human bone marrow and immune environment, enabling more predictive testing of cancer immunotherapy success in patients, including CAR T cell therapies.

3 min. read

Survey finds some confusion over mammogram guidelines

Survey finds some confusion over mammogram guidelines

A recent survey question by the Annenberg Public Policy Center shows that some Americans appear to be confused about when women with an average risk of breast cancer should begin a regimen of regular mammograms. The survey finds that nearly half of those surveyed know that age 40 is when women at an average risk of breast cancer should begin to have mammograms every other year, and 11% are not sure.

Gene therapy may slow loss of motor function in ALS
A microscopic rendering of a neuromuscular junction.

Image: Koto_Feja via Getty Images

Gene therapy may slow loss of motor function in ALS

Researchers at the Perelman School of Medicine and Children's Hospital of Philadelphia used RNA interference to silence a key protein that causes ALS, showing promise for treating the devastating neurodegenerative disease.

Kelsey Geesler

Penn engineers turn toxic fungus into anti-cancer drug
Qiuyue Nie and Maria Zotova, from left, purify samples of the fungus in a lab.

First author Qiuyue Nie (left) and coauthor Maria Zotova purify samples of the fungus.

(Image: Bella Ciervo)

Penn engineers turn toxic fungus into anti-cancer drug

Penn-led researchers have isolated a new class of molecules from Aspergillus flavus, a toxic crop fungus, and modified it into a promising cancer-killing compound

Ian Scheffler

2 min. read

Penn Medicine outreach addresses health-related social needs
A volunteer with Penn Medicine SHARE Food Program hands a box of food to a bike courier.

Image: Courtesy of Penn Medicine Magazine

Penn Medicine outreach addresses health-related social needs

For five years, Penn Medicine’s Social Needs Response Team has connected patients to vital support foundational to good health.

From Penn Medicine Magazine

2 min. read

Innovative program jointly launched by Independence Blue Cross and Penn Medicine accelerates access to outpatient scans

Innovative program jointly launched by Independence Blue Cross and Penn Medicine accelerates access to outpatient scans

A joint program from Independence Blue Cross (IBX) and Penn Medicine gets patients on the path to care and a diagnosis faster and to save both providers and IBX time on prior authorization requests for outpatient scans (such as, CT, PET, and nuclear medicine scans, MRI and echocardiograms). Launched in 2023, the success of the program has driven IBX to expand the program to other network providers.

New rules for methadone doses at home did not increase overdoses

New rules for methadone doses at home did not increase overdoses

LDI senior fellows have studied the impact of the federal policy change for patients to access take-home doses and recommend that policymakers at both the state and federal levels should support the continued expansion of flexible take-home methadone policies, citing the benefits of patient autonomy and the evidence that take-home doses did not increase methadone-involved overdose deaths overall.

Nancy A. Speck honored for pioneering research in hematology

Nancy A. Speck honored for pioneering research in hematology

Speck, the John W. Eckman Professor in Medical Science II and chair of the department of Cell and Developmental Biology in the Perelman School of Medicine, has been named the 2025 recipient of the E. Donnall Thomas Lecture and Prize from the American Society of Hematology.