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Study finds children’s health broadly declining in the U.S.
Four teens looking unhappy on a couch.

Image: Maskot via Getty Images

Study finds children’s health broadly declining in the U.S.

Using data from 2007 to 2023, researchers from Penn Medicine and CHOP found measures like mental health and obesity, as well as infant and child mortality rose. They urge policy interventions and improved societal infrastructure to prioritize health of the country’s youngest generation.

4 min. read

AI-driven discovery of hundreds of potential antibiotics
Venom on the Fang of a Diamondback Rattlesnake

Image: McDonald Wildlife Photography Inc. via Getty Images

AI-driven discovery of hundreds of potential antibiotics

Research from the lab of César de la Fuente on an AI-powered screen of global venom libraries uncovers dozens of promising drug candidates.

Eric Horvath

2 min. read

How discoveries become cures
Two doctors in white lab coats in a lab.

Image: Margo Reed

How discoveries become cures

Public investments in biomedical research have an outsized effect, driving new scientific insights, economic growth, and ultimately treatments and cures.

3 min. read

Genetic testing beneficial in critically ill adults
Pipette adding a sample to a petri dish with a DNA profile in the background.

Image: Ten Image/Science Photo Library via Getty Images

Genetic testing beneficial in critically ill adults

Penn Medicine researchers have identified genetic conditions in a large percent of adults admitted to the intensive care unit, dispelling the belief that genetic testing only benefits a pediatric population.

3 min. read

New Penn Vet study uncovers a key guardian of gut health and metabolism
Oriol Sunyer pointing to rainbow trout, the fish species used for the reported study.

Oriol Sunyer points out rainbow trout, the fish species used for the reported study.

(Image: Courtesy of Penn Vet)

New Penn Vet study uncovers a key guardian of gut health and metabolism

Researchers at the School of Veterinary Medicine unveil the critical role of secretory immunoglobulin M (sIgM) in maintaining microbiota balance, regulating metabolism, and protecting against disease.

Martin Hackett

2 min. read

Transforming CAR T treatment: ‘Leukemia-on-a-chip’
The actual chip of human leukemia bone marrow where chambers and channels were filled with food dyes.

The actual chip of human leukemia bone marrow where chambers and channels were filled with food dyes.

(Image: NYU Tandon Applied Micro-Bioengineering Laboratory/Courtesy of Weiqiang Chen)

Transforming CAR T treatment: ‘Leukemia-on-a-chip’

In a collaborative effort with NYU, Penn researchers have helped pioneer a novel 3D platform that mimics the human bone marrow and immune environment, enabling more predictive testing of cancer immunotherapy success in patients, including CAR T cell therapies.

3 min. read

Survey finds some confusion over mammogram guidelines

Survey finds some confusion over mammogram guidelines

A recent survey question by the Annenberg Public Policy Center shows that some Americans appear to be confused about when women with an average risk of breast cancer should begin a regimen of regular mammograms. The survey finds that nearly half of those surveyed know that age 40 is when women at an average risk of breast cancer should begin to have mammograms every other year, and 11% are not sure.

Gene therapy may slow loss of motor function in ALS
A microscopic rendering of a neuromuscular junction.

Image: Koto_Feja via Getty Images

Gene therapy may slow loss of motor function in ALS

Researchers at the Perelman School of Medicine and Children's Hospital of Philadelphia used RNA interference to silence a key protein that causes ALS, showing promise for treating the devastating neurodegenerative disease.

Kelsey Geesler

Penn engineers turn toxic fungus into anti-cancer drug
Qiuyue Nie and Maria Zotova, from left, purify samples of the fungus in a lab.

First author Qiuyue Nie (left) and coauthor Maria Zotova purify samples of the fungus.

(Image: Bella Ciervo)

Penn engineers turn toxic fungus into anti-cancer drug

Penn-led researchers have isolated a new class of molecules from Aspergillus flavus, a toxic crop fungus, and modified it into a promising cancer-killing compound

Ian Scheffler

2 min. read