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mRNA Research
From a pandemic, scientific insights poised to impact more than just COVID-19
From a pandemic, scientific insights poised to impact more than just COVID-19
Pivoting to study SARS-CoV-2, many scientists on campus have launched new research projects that address the challenges of the pandemic but also prepare us to confront future challenges.
Vaccine-like mRNA injection can be used to make CAR T cells in the body
Vaccine-like mRNA injection can be used to make CAR T cells in the body
An experimental immunotherapy can temporarily reprogram patients’ immune cells to attack heart fibroblast cells via only a single injection of mRNA.
From foundational discoveries to profound impact
From foundational discoveries to profound impact
How decades of mRNA research at Penn made powerful new COVID-19 vaccines possible—and opened a new vista for future discoveries.
Drew Weissman and Katalin Karikó receive 2021 Lasker Award
Drew Weissman and Katalin Karikó receive 2021 Lasker Award
Weissman and Karikó’s mRNA technology is recognized for enabling rapid development of highly effective COVID-19 vaccines
Penn engineers will develop on-demand, on-site mRNA manufacturing
Penn engineers will develop on-demand, on-site mRNA manufacturing
With an NSF grant, Penn Engineering researchers are developing a new manufacturing technique that would be able to produce mRNA sequences in a way that removes the need for cryogenic temperatures.
mRNA COVID-19 vaccines induce T-cell responses in multiple sclerosis patients
mRNA COVID-19 vaccines induce T-cell responses in multiple sclerosis patients
Research from Penn Medicine shows mRNA COVID-19 vaccines are effective at inducing T-cell responses in multiple sclerosis patients who receive B cell-depleting Infusions even if their antibody responses are diminished.
2022 Breakthrough Prize in Life Sciences awarded to mRNA pioneers Drew Weissman and Katalin Karikó
2022 Breakthrough Prize in Life Sciences awarded to mRNA pioneers Drew Weissman and Katalin Karikó
Weissman and Karikó are honored for engineering modified RNA technology which enabled rapid development of effective COVID-19 vaccines.
Penn mRNA researchers Drew Weissman and Katalin Karikó awarded the 2021 Albany Prize
Penn mRNA researchers Drew Weissman and Katalin Karikó awarded the 2021 Albany Prize
For their landmark research that set a foundation for the mRNA SARS-CoV-2 vaccines, Drew Weissman and Katalin Karikó have been selected to receive the prize after decades of work.
COVID-19 mRNA vaccine that uses fundamental Penn technology receives FDA approval
COVID-19 mRNA vaccine that uses fundamental Penn technology receives FDA approval
Pfizer/BioNTech’s vaccine to prevent COVID-19 uses fundamental modified mRNA technology created by Drew Weissman and Katalin Karikó at the Perelman School of Medicine.
Penn study details robust T-cell response to mRNA COVID-19 vaccines
Penn study details robust T-cell response to mRNA COVID-19 vaccines
The results underline the importance of a second dose and include implications for booster shots.
In the News
The Hill
mRNA vaccine by UPenn scientists could manage bird flu outbreak
Researchers led by Scott Hensley of the Perelman School of Medicine have collaborated with Drew Weissman to develop an mRNA vaccine to treat the H5N1 avian flu.
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6ABC.com
Penn Medicine creates human bird flu vaccine
Researchers at Penn Medicine have created a human bird flu vaccine using mRNA, the same platform as the COVID-19 vaccine.
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Fast Company
Researchers are working on a new mRNA vaccine—this time for bird flu
Researchers led by Scott Hensley of the Perelman School of Medicine are developing an mRNA vaccine for the H5N1 avian flu with support from Nobel Prize cowinner Drew Weissman.
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Deutsche Welle
A vaccine for pancreatic cancer?
Drew Weissman of the Perelman School of Medicine comments on the efficacy of a potential pancreatic cancer vaccine.
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Scientific American
Pancreatic cancer vaccine shows promise in small initial trial
Drew Weissman of the Perelman School of Medicine is supportive of findings about a pancreatic cancer vaccine, though he says larger studies are needed to determine effectiveness.
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