Study reveals inequities in access to transformative CAR T cell therapy Image: iStock/PeopleImages Study reveals inequities in access to transformative CAR T cell therapy Penn Medicine researchers have assessed the percentage of patients from minority health populations and reveal inequities in access to transformative CAR T cell therapy.
A hopeful time for Cryptosporidium research A lot of research progress has been over the past decade on Cryptosporidium, a single-celled parasite that is one of the leading causes of deadly diarrheal disease, and Penn Vet professors brought together researchers and clinicians from around the world for a conference. (Image: Muthgapatti Kandasamy and Boris Striepen) A hopeful time for Cryptosporidium research Boris Striepen of Penn Vet organized the First Biennial Cryptosporidium Meeting, bringing together researchers and clinicians from around the world to discuss the problems and progress around the parasite and the diarrheal disease it causes.
Soft support can make unexpectedly stable glass Image: iStock / Gloria Sonda Soft support can make unexpectedly stable glass A team of researchers from Penn and the Brookhaven National Laboratory find a new way to manufacture stable glass.
Reading James Baldwin for a 21st century world Nuri Yi, a Lotus member and second-year grad student in the Department of Biology in the School of Arts & Sciences, leads a discussion of Baldwin’s work at Kelly Writers House.nocred Reading James Baldwin for a 21st century world To commemorate Baldwin’s approaching centennial, the Lotus Collective is hosting weekly readings and discussions of his work at Kelly Writers House.
Structural elements of archaea Archaea, a unique domain of life, were discovered in the 1970s in extreme environments such as hot springs and salty lakes, with notable early studies conducted in locations like Yellowstone National Park in the United States. Initially considered unusual bacteria, their distinct genetics and biochemistry led to their recognition as a separate domain, emphasizing microbial diversity and evolutionary complexity. (Image: iStock / rmbarricarte) Structural elements of archaea Researchers shed light on archea, a single cell microorganism, to discover how proteins determine what shape a cell will take and how that form may function.
When do stereotypes undermine indirect reciprocity? iStock / bakhtiar_zein When do stereotypes undermine indirect reciprocity? Researchers from Penn and Princeton develop a model to evaluate how reputation and indirect reciprocity affects cooperative behaviors.
‘Switchable’ bispecific antibodies pave way for safer cancer treatment Bispecific T cell engagers are emerging as a powerful class of immunotherapy to treat cancer but are sometimes hindered by unwanted outcomes, such as on-target, off-tumor toxicity; cytokine release syndrome; and neurotoxicity. Now, researchers Penn researchers have developed a novel “switchable” bispecific T cell engager that mitigates these negative effects by co-opting a drug already approved by the FDA. (Image: iStock / CIPhotos) ‘Switchable’ bispecific antibodies pave way for safer cancer treatment Immunotherapy utilizing an FDA-approved drug has enabled Penn researchers to develop a novel switchable bispecific T cell engager that mitigates negative outcomes of immunotherapy.
After #MeToo, sexual assault survivors still fight to be believed Image: Courtesy of Annenberg School for Communication After #MeToo, sexual assault survivors still fight to be believed In their new book, Annenberg School for Communication Dean Sarah Banet-Weiser and former postdoctoral fellow Kathryn Claire Higgins explore the work victims of sexual violence go through to be believed.
The mission to get Pennsylvanians online Image: ronstik for Adobe Stock The mission to get Pennsylvanians online The Pennsylvania Broadband Research Institute, a collaboration between Penn and Penn State, looks for ways to bridge the digital divide in the state—and the rest of the nation.
Researchers breathe new life into lung repair Respiratory diseases like influenza and COVID-19 drive inflammatory responses that can cause long-term damage to the lungs and can be difficult to treat. Now, by using techniques that deliver mRNA via lipid nanoparticles, researchers led by Andrew Vaughan of the School of Veterinary Medicine were able to greatly enhance modes of repair for damaged blood vessels in the lung, leading to improved oxygen saturation. (Image: iStock/Mohammed Haneefa Nizamudeen) Researchers breathe new life into lung repair A collaborative effort from teams across Penn culminates in new techniques to repair lung tissue after damage from flu and COVID-19.