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New biomarkers can help target treatment for chronic skin disease
Microscopic view of granulomatous tissue.

Cellular view of granulomatous tissue.

(Image: iStock/Md Saiful Islam Khan)

New biomarkers can help target treatment for chronic skin disease

Researchers at Penn Medicine have found a pathway in certain lymphoid cells that, once targeted, inhibit granulomas from forming in patients with sarcoidosis.

Alex Gardner

Gene therapy trial sees massive improvement in vision
Closeup view of an eyeball with a vision test graphic.

Image: iStock/murat4art

Gene therapy trial sees massive improvement in vision

Patients with a rare disease affecting their sight have experienced quick vision improvements that sustained for the full yearlong Penn Medicine study, with some experiencing a 10,000-fold improvement in their vision.
Weight management drug does not increase risk of depression or suicidal behavior
A person opening the top of a semaglutide prescription pen.

Image: iStock/imyskin

Weight management drug does not increase risk of depression or suicidal behavior

In new clinical trials, researchers from Penn Medicine find that for people without known major psychopathology, taking semaglutide for weight loss are at no increased risk of mental health issues.

From Penn Medicine News

Boosting the frequency of sound waves to make the next generation of wireless devices
Researchers in a clean room pointing at a microscope.

Under the guidance of Yue Jiang(left), a Ph.D. candidate in the Charlie Johnson research group in the School of Arts & Sciences, Vincent Kerler (right) conducted this work through the Penn Undergraduate Researching Mentoring Program, a 10-week opportunity from the Center for Undergraduate Research and Fellowships. The program provides rising second- and third-year students with $5,000 awards to work alongside Penn faculty.

nocred

Boosting the frequency of sound waves to make the next generation of wireless devices

Vincent Kerler, a second-year student in the College of Arts and Sciences, spent the summer running simulations as part of Charlie Johnson’s research on topological insulators.
The mechanics of collaboration
Portrait of Xinlan Emily Hu

nocred

The mechanics of collaboration

Penn Ph.D. student Xinlan Emily Hu leads a group of budding engineers and social scientists who study communication across teams. The group has developed a new toolkit aimed at helping researchers analyze and measure teamwork.
NASA’s Roman Space Telescope will investigate the history of galaxies
artist's concept of the Andromeda galaxy's stellar halo, depicted with exaggerated brightness and density, highlighting the extent of this faint and loosely connected collection of stars that surrounds the galaxy.

Robyn Sanderson and Adrien Thob of the School of Arts & Sciences are part of a team of astronomers using NASA’s upcoming Nancy Grace Roman Space Telescope to uncover the “fossil record” of the universe as they look to clues to unearth key insights into its formation.

(Image: Courtesy of NASA, Ralf Crawford (STScI))

NASA’s Roman Space Telescope will investigate the history of galaxies

Robyn Sanderson and collaborators are unearthing the history of the universe’s formation by looking for clues that reveal its “galactic fossil record.”
Court no-shows: A systemic issue
The courtyard at City Hall in Philadelphia.

Image: iStock/Alexandre Tziripouloff

Court no-shows: A systemic issue

Penn Carey Law professor Sandy Mayson has found that failure-to-appear plays a central role in criminal case processing in Philadelphia.

From Penn Carey Law

1 min. read

Uncovering new antibiotics inside the human gut
Microscopic rendering of bacterial in the small intestines.

Image: iStock/ChrisChrisW

Uncovering new antibiotics inside the human gut

Researchers from Penn Engineering, led by César de la Fuente, have leveraged AI to discover dozens of potential new antibiotics in the human gut microbiome.

Ian Scheffler

A modified peptide shows promise for fighting tumors
Tumor microenvironment.

A collaborative team of researchers including scientists from the School of Veterinary Medicine and Perelman School of Medicine show how a modified peptide can successfully target the immunosuppressive tumor microenvironment.

(Image: iStock/Marcin Klapczynski)

A modified peptide shows promise for fighting tumors

Researchers in Penn Vet led a collaborative study that demonstrates how a modified peptide normalizes tumor vasculature and enhances various cancer treatments.