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Health & Medicine

Examining asthma with human lung-on-a-chip technology
A chip with asthma cells being held up in a dark, neon-colored laboratory environment

A bioengineered “asthma-on-a-chip” platform. (Image: Courtesy of Penn Engineering)

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Examining asthma with human lung-on-a-chip technology

Researchers at Penn Engineering developed an ‘asthma-on-a-chip’ system that mimics the mechanical stresses experienced by human airways during an asthma attack. The innovation enables scientists to probe how unhealthy lung tissue responds to compression in ways previously impossible to observe directly in patients.

Melissa Pappas , From Penn Engineering

2 min. read

What a ‘silenced’ chromosome can tell us about autoimmunity
female chromosomes

Image: Kateryna Kon/Science Photo Library

What a ‘silenced’ chromosome can tell us about autoimmunity

Systemic lupus erythematosus (SLE), the most common form of lupus, is an autoimmune disorder that occurs more frequently in women. Having multiple X chromosomes has been associated with an increased risk of developing lupus; however, the reason for this link is still not fully understood and may involve how X chromosomes are regulated in female immune cells.

3 min. read

New mRNA vaccine platform could expand global vaccine access

New mRNA vaccine platform could expand global vaccine access

A Penn Medicine-created vaccine platform swaps out lipid nanoparticles with a different kind of nanoparticle to simplify manufacturing, making the vaccines easier and more cost-effective to produce, transport, store, and distribute.

Transforming healthcare logistics with low-cost AI
 Bustling day outside a hospital.

Credit: mtcurado

Transforming healthcare logistics with low-cost AI

Researchers from the Wharton School and Penn Engineering partnered with Sierra Leone’s government to build a low-cost AI tool that optimizes the allocation of essential medical supplies across the country. By accounting for missing data and navigating unexpected supply chain disruptions, the system ensures life-saving products reach the clinics that need them most.

4 min. read

The public health impacts of floods
The Philly freeway submerged in water after flooding from a hurricane.

Image: Philippe Gerber via Getty Images

The public health impacts of floods

Cheryl Bettigole, executive director of the Penn Center for Public Health and former health commissioner of Philadelphia, discusses the many ways communities are affected by floods

3 min. read

Support for trainees ensures a bright future for BRCA science

Support for trainees ensures a bright future for BRCA science

The Basser Center for BRCA Postdoctoral Fellowship Program, founded by Ilana Katz Sand and Michael Sand, provides support for one postdoctoral fellow for three years or the last two years of training for a clinical fellow.

Finding cell subgroups could spur retinal cell transplant success

Finding cell subgroups could spur retinal cell transplant success

Researchers at the Perelman School of Medicine have uncovered a new understanding of retinal cell development which may help pave the way for future retina transplants, and could restore sight to people whose conditions currently have no effective treatments.

AI in nursing raises questions about safety, ethics, and human care
A nurse typing on a desktop computer.

Image: Ugur Karakoc via Getty Images

AI in nursing raises questions about safety, ethics, and human care

A new paper from Penn’s School of Nursing explores the potential benefits and challenges involved in the AI automation of the clinical nursing space.

Hoag Levins

2 min. read