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Health & Medicine

Getting to the root of root canals
Person receiving treatment in a dental clinic.

Image: Courtesy of Penn Dental Medicine/Peter Olson Photography

Getting to the root of root canals

Penn researchers use iron oxide nanozymes to treat infections during root canals with fewer adverse effects than clinical gold standard while also promoting tissue healing.
With hemophilia B, a lifetime of worry eased with one infusion
An infusion bag hanging in a hospital room.

Image: iStock/Isaac Lee

With hemophilia B, a lifetime of worry eased with one infusion

The first Penn Medicine patient to receive an FDA-approved new gene therapy for hemophilia B can now stop regular prophylactic clotting factor injections.

From Penn Medicine News

Pursuing vaccines to stop celiac disease
A researcher holding a vaccine vial in a lab next to a microscope.

Image: iStock/nuttapong punna

Pursuing vaccines to stop celiac disease

Scientists at Penn’s Institute for RNA Innovation are using messenger RNA to stop the immune response that triggers celiac disease symptoms.

Alex Gardner

Researchers create genetic map tied to kidney disease
microscopic rendering of DNA strands.

Image: iStock/TanyaJoy

Researchers create genetic map tied to kidney disease

The creation of the most complete map of more than 1,000 genes that influence kidney function could help experts diagnose and design targeted treatments for kidney disease.

Alex Gardner

Rate of suicide higher in individuals with headaches
A person holding their head in pain near a window.

Image: iStock/Ake Ngiamsanguan

Rate of suicide higher in individuals with headaches

New research from Penn Medicine finds that suicide attempt and completion is highest among individuals with headaches from head injuries, but also elevated in individuals with mild headaches.

Kelsey Geesler

Catherine and Anthony Clifton make transformational gift to accelerate patient care, research, and education at Penn Medicine
Seven people including Penn President J. Larry Jameson, Catherine and Anthony Clifton, Kevin Mahoney, and Jon Epstein.

From left to right, Penn Medicine Board Chair Dhan Pai; Interim Penn President J. Larry Jameson; donors Catherine and Anthony Clifton; Hospital of the University of Pennsylvania CEO Regina Cunningham; University of Pennsylvania Health System CEO Kevin B. Mahoney; and Interim EVP of the University for the Health System and Perelman School of Medicine Dean Jonathan A. Epstein.

(Image: Eddy Marenco)

Catherine and Anthony Clifton make transformational gift to accelerate patient care, research, and education at Penn Medicine

The Pavilion will be renamed in recognition of the Cliftons’ historic philanthropic commitment, one of the largest ever to name a U.S. inpatient hospital building.
No evidence that CAR T cell therapy causes secondary cancers
Person in gloves holding a medical bag of liquids.

Image: Courtesy of Penn Medicine

No evidence that CAR T cell therapy causes secondary cancers

In a new study, researchers at Penn Medicine looked for—and did not find—examples where the process of generating CAR T cells caused malignancy.

Kelsey Geesler

Borrowing nature’s blueprint: How scientists replicated bone marrow
A chip with bioengineered bone marrow.

The new chip will allow for automated experiments, and can be connected to chip-based models of other organ systems, like the lungs.

(Image: Dan Huh)

Borrowing nature’s blueprint: How scientists replicated bone marrow

A collaborative research team from Penn Engineering, Penn Medicine, and the Children’s Hospital of Philadelphia have developed a chip that mimics human bone marrow.

Ian Scheffler