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This Penn heart patient is a 9-year-old boxer dog named Sophie
sophie the boxer with a penn vet doctor

This Penn heart patient is a 9-year-old boxer dog named Sophie

Sophie underwent a cardiac ablation procedure in a Perelman School of Medicine translational research lab to treat her arrhythmia—the first time a dog with her diagnosis received such a treatment. Veterinary cardiologist Anna Gelzer says of the collaboration, “It’s the best of both worlds.”

Katherine Unger Baillie

Using science to make cities safer and healthier
Two people standing in front of a fenced-in vacant lot, one leaning against the fence, the other standing with arms crossed.

Penn Medicine’s Eugenia South, seen here with John MacDonald of the Department of Criminology, studies the effect of chronic stress and neighborhood environment on health outcomes. South’s latest pilot, Nurtured in Nature, follows work from the pair showing that cleaning up vacant lots leads to a signifiant decrease in gun violence and less stress for local residents. (Pre-pandemic photo)

Using science to make cities safer and healthier

In a Q&A, criminologist John MacDonald discusses his new book, grounded in years of research on the positive effects of remediation like fixing up abandoned lots and houses.

Michele W. Berger

Inspiring young women in STEM
a group of people seated at a circle of chairs talking to each other

Inspiring young women in STEM

Over two days, nearly two dozen female STEM role models at Penn welcomed more than 100 high school students and teachers to campus as part of the Girls Advancing in STEM (GAINS) Initiative Conference on campus.

Erica K. Brockmeier

How does opioid exposure affect brain development in young children?
Two people standing in a building entryway. Windows are on their left, a yellow wall with a portrait are on their right. They're both looking into the camera and smiling.

The new NIH-funded work from researchers Dylan Tisdall of Penn Medicine and Allyson Mackey of the School of Arts and Sciences will work to develop an MRI method geared specifically to three- to five-year-olds and calculate how exposure to opioids can impede neurocognitive development of children in that age range.

How does opioid exposure affect brain development in young children?

That’s the question Allyson Mackey and Dylan Tisdall hope to answer, through a new grant from an NIH initiative focused on addiction research.

Michele W. Berger

Advancing algorithmic care
a person standing in front of a large room of people the viewpoint from the back of a tall set of bleachers in an industrial room

Advancing algorithmic care

Experts from Penn share their perspectives on the role of advanced algorithms and AI in health care and what the future holds for digital health technologies.

Erica K. Brockmeier

An easier way of sneaking antibodies into cells
rendering of an antibody about to go through the membrane of a cell

Getting a complex protein like an antibody through the membrane of a cell without damaging either is a longstanding challenge in the life sciences. (Image: Penn Engineering)

An easier way of sneaking antibodies into cells

Penn Engineers have found a plug-and-play solution that makes antibodies compatible with the delivery vehicles commonly used to ferry nucleic acids through the membrane of a cell without damaging either.

Penn Today Staff

Basser Center takes aim at BRCA
basser center lab

Basser Center takes aim at BRCA

Twenty-five years after the discovery of genetic mutations that dramatically increase cancer risk, the Penn Medicine’s Basser Center for BRCA is building scientific knowledge alongside public awareness about BRCA-related cancers.

Katherine Unger Baillie

The science of sensations
Smiling scientist stands in a lab

Ishmail Abdus-Saboor has carved out a path studying the biology of touch, pain, and itch.

The science of sensations

To confront the ills of the opioid epidemic, scientists must develop a fundamental understanding of the biology of pain. Biologist Ishmail Abdus-Saboor’s work is setting the stage for screening alternative drugs and uncovering new pathways that an opioid-alternative could target.

Katherine Unger Baillie

Comprehensive dental care for a vulnerable population
Two Penn Dental students provide dental care to a patient in a dental chair.

Comprehensive dental care for a vulnerable population

In a new clinic at the School of Dental Medicine, refugees who survived torture are having all of their dental needs met by students and faculty.

Katherine Unger Baillie

Fruit flies’ microbiomes shape their evolution
fruit fly close-up on a piece of vegetation

An ambitious outdoor experiment in fruit flies at Pennovation Works revealed that an altered microbiome can drive evolutionary change. (Photo: Seth Rudman)

Fruit flies’ microbiomes shape their evolution

In just five generations, an altered microbiome can lead to genome-wide evolution in fruit flies, according to new research led by Paul Schmidt and postdoc Seth Rudman of the School of Arts and Sciences.

Katherine Unger Baillie