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Most who meet proposed CTE criteria do not show disease signs at autopsy
 Gloved hand holding a scan of four brains

Image: pangoasis via Getty Images

Most who meet proposed CTE criteria do not show disease signs at autopsy

New research from Penn Medicine finds proposed traumatic encephalopathy syndrome criteria often don’t match CTE pathology at autopsy, raising concerns about misdiagnosis and potential mental health impacts for at-risk groups.

Kelsey Geesler

Specialized RNA molecules could counter ALS neurodegeneration
Microscopic view of mRNA

Image: Courtesy of Penn Medicine

Specialized RNA molecules could counter ALS neurodegeneration

Researchers at Penn Medicine have discovered short RNA chaperones that bind to the primary target of ALS, restore its function, and protect motor neurons in a preclinical model, pointing toward a new RNA-based therapeutic strategy.

From Penn Medicine News

2 min. read

Bringing hope to uterine health patients

Bringing hope to uterine health patients

Physician-scientist Kate O’Neill directs innovative research that helps people suffering from infertility, endometriosis, and other issues build families and have excellent quality-of-life.

1 min. read

Empowering unhoused patients through comprehensive eye care
From left to right: Justin Wang, Janine Haros, and Eric Lee in a clinical room at the Scheie Eye Institute, holding documents and smiling together

Justin Wang (left), Janine Haros (center), and Eric Lee (right) in a clinical room at the Scheie Eye Institute, holding documents and smiling together.

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Empowering unhoused patients through comprehensive eye care

Penn fourth-years Eric Lee, Janine Haros, and Justin Wang will use a President’s Engagement Prize to elevate vision health in unhoused individuals across Philadelphia through free eye screenings, tailored care coordination, and interactive patient education.

4 min. read

Using AI to help predict cardiac arrests
A doctor looking at EKG heart data.

Image: SimpleImages via Getty Images

Using AI to help predict cardiac arrests

A Penn Engineering and Penn Medicine team built CAMEL, an artificial intelligence model that forecasts dangerous cardiac rhythms before they strike. Their findings pave the way for a new era of real-time, predictive heart care.

2 min. read

Voting is linked to living longer
African American person tearing off an I Voted Today sticker

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Voting is linked to living longer

A new study co-authored by SP2’s Femida Handy shows that voting is associated with reduced mortality risk in older adults.

2 min. read

Penn Medicine, CHOP team awarded Breakthrough Prize for developing gene therapy for inherited blindness
Jean Bennett and Albert Maguire

Physician-scientists Jean Bennett and Al Maguire (right and left, respectively, pictured in their home), and Katherine High received the 2026 Breakthrough Prize in Life Sciences for their trailblazing work on the first FDA-approved gene therapy for an inherited condition, which dramatically improves sight in people with a form of blindness called Leber congenital amaurosis.

(Image: Peggy Peterson)

Penn Medicine, CHOP team awarded Breakthrough Prize for developing gene therapy for inherited blindness

Jean Bennett, Albert Maguire, and Katherine High have been honored for their trailblazing work on the first FDA-approved gene therapy for an inherited condition.

From Penn Medicine News , Frank Otto

2 min. read