Medicine | Penn Today

Molecular mechanics behind heart cell restructuring revealed

Two new Penn Medicine studies show that microtubules help determine how the heart changes shape under stress, and a common signaling pathway acts as a key controller of where the building materials for these cells’ growth are delivered inside them; the findings point to possible new ways to address causes of heart failure.

New CAR T treatment opens doors for kidney patients

An early Penn Medicine trial demonstrates CAR T cells can safely desensitize even the most challenging transplant candidates.

2 min. read

Mass. has new limits on insurers’ much-hated prior authorizations. Here’s what to know

“For providers, there will still be a substantial amount of uncertainty and administrative burden related to prior authorization” because of the differing rules based on insurance type, says Aaron Schwartz of the Perelman School of Medicine.

GLP-1 use linked to lower breast cancer incidence in large cohort study

A retrospective analysis of more than 110,000 women between the ages of 45 and 80 found that those who take GLP-1 medications are about 30% less likely to develop breast cancer than those who do not take GLP-1 medications.

2 min. read

A Philly man didn’t know if he’d ever get off the kidney transplant waiting list. CAR T made it happen

“Since its first use in a 2010 clinical trial involving leukemia patients at Penn, efforts to broaden CAR-T’s applications have advanced slowly. The therapy has not proven effective against solid cancers, although some studies have shown potential.”

Nurses practice how to talk to patients about properly storing medications

To deliver hospital-level care at home, practice makes perfect

Years of planning come to fruition as Penn Medicine’s Hospital at Home teams test run a new era of patient care devoted to better outcomes and fewer readmissions.

2 min. read

Jacob R. Gardner, César de la Fuente and Marcelo Torres, holding a 3D-printed example of the kind of antibiotic peptide they generated

An AI tool to speed antibiotic discovery

APEX is an AI model that predicts whether or not a given peptide is likely to have antimicrobial properties. Now, APEXGo can identify antibiotic candidates with laboratory activity against disease-causing bacteria, simply by searching large datasets.

2 min. read

Penn’s Transplant House outdoor entrance.

 A home away from home for transplant patients and families

Penn’s Clyde F. Barker Penn Transplant House offers a comforting and affordable refuge for transplant patients and families—with community and hope.

2 min. read

Major gaps in online info for patients about AI and cancer

In a new Penn Medicine study, researchers screened web pages to understand how patients are using AI in their searches in an effort to work with the emerging technology to offer more accessible, high-quality resources.

Samuel Nathan, a doctor from Ghana, and Dan Menéndez, a U.K.-trained physician

From clinic to classroom: How two physicians are rethinking healthcare through business

The Wharton MBA and Lauder Institute MA in International Studies joint-degree program emphasizes regional expertise, culture, and policy so its students can learn to develop health care solutions.

2 min. read

Filters

Molecular mechanics behind heart cell restructuring revealed

New CAR T treatment opens doors for kidney patients

Mass. has new limits on insurers’ much-hated prior authorizations. Here’s what to know

GLP-1 use linked to lower breast cancer incidence in large cohort study

A Philly man didn’t know if he’d ever get off the kidney transplant waiting list. CAR T made it happen

To deliver hospital-level care at home, practice makes perfect

An AI tool to speed antibiotic discovery

A home away from home for transplant patients and families

Major gaps in online info for patients about AI and cancer

From clinic to classroom: How two physicians are rethinking healthcare through business

 A home away from home for transplant patients and families