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Neuroscience

Who, What, Why: Katelyn Candido on improving surgical procedures and keeping health care human-first
Katelyn Candido standing next to a wall, smiling and facing forward with arms crossed, wearing a white coat and blue scrubs in the Perelman School of Medicine

Katelyn Candido, a second-year medical student at PSOM and aspiring neurosurgeon, researches a novel tool’s utility for improving surgical precision. Informed by experiences as a first-generation Hispanic student, Candido also deeply values the human-centered side of medicine, helping drive equitable care in Philadelphia and beyond.

nocred

Who, What, Why: Katelyn Candido on improving surgical procedures and keeping health care human-first

Second-year medical student Katelyn Candido shares insight into her research project on a promising tool for improving surgical precision and efficiency, and why she aims to drive equitable patient care through a career in neurosurgery.

3 min. read

No brain, no gain: Neuronal activity enhances benefits of exercise
Rendering of the human body on a bicycle and the brain and skeletal system highlighted.

Image: Sciepro/Science Photo Library via Getty Images

No brain, no gain: Neuronal activity enhances benefits of exercise

Research led by Penn neuroscientist J. Nicholas Betley and collaborators finds that hypothalamic neurons are essential for translating physical exertion into endurance, potentially opening the door to exercise-mimicking therapies.

5 min. read

Gene therapy ‘switch’ may offer non-addictive pain relief
Scan of human amygdala.

Image: nopparit via Getty Images

Gene therapy ‘switch’ may offer non-addictive pain relief

In a preclinical study, Penn Medicine researchers have uncovered a new gene therapy that targets only pain signals while leaving the rest of the brain untouched.

Eric Horvath

2 min. read

20 breakthroughs of 2025
Masoud Akbarzadeh holding up one of the fabricated materials.

The Polyhedral Structures Laboratory is housed at the Pennovation Center and brings together designers, engineers, and computer scientists to reimagine the built world. Using graphic statics, a method where forces are mapped as lines, they design forms that balance compression and tension. These result in structures that use far fewer materials while remaining strong and efficient.

(Image: Eric Sucar)

20 breakthroughs of 2025

From ancient tombs and tiny robots to personalized gene editing and AI weather models, Penn’s 2025 research portfolio showed how curiosity—paired with collaboration—moves knowledge into impact and stretches across disciplines and continents.

5 min. read