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Getting gene therapy to the brain
Illustration of brain with DNA double helix

Crossing the blood-brain barrier to treat the whole brain has been a challenge for researchers aiming to treat inherited neurodegenerative disease. The results from a study in a large animal model offer “a big advance” in this pursuit, says John Wolfe of Penn Vet, Penn Medicine, and CHOP.

Getting gene therapy to the brain

Using a large animal model of genetic brain disease, researchers led by John H. Wolfe of the School of Veterinary Medicine, Perelman School of Medicine, and Children’s Hospital of Philadelphia delivered an effective treatment across the blood-brain barrier to correct the whole brain.

Katherine Unger Baillie

What would it take to make the Delaware ‘swimmable’?
delaware river with ben franklin bridge in background

What would it take to make the Delaware ‘swimmable’?

With funding from the William Penn Foundation, the Water Center at Penn is investigating questions of water quality, access, and equity.

Katherine Unger Baillie

‘Self-eating’ stem cell process may be the key to new regenerative therapies
stem cells in autophagy

A translucently colored embryonic stem (ES) cell and its differentiating derivatives. (Image: Penn Medicine News)

‘Self-eating’ stem cell process may be the key to new regenerative therapies

A Penn study uncovers new roles of chaperone-mediated autophagy in how stem cells repair or regenerate damaged organs.

From Penn Medicine News

Russia, bounties, and the U.S. elections
The Russian flag cracked diagonally overlaps with the US flag behind it

Russia has been making headlines in the U.S. this election cycle, but it's not the meddling narrative of 2016.

Russia, bounties, and the U.S. elections

Amid allegations of Russian bounties on U.S. soldiers and of hackers trying to steal vaccine research, Penn Today spoke to two experts to get their take and how the developments play into the U.S. presidential election cycle.

Kristen de Groot

Post-pandemic retirement: Can we build more resilient systems?
Older couple sitting on a couch looking at a laptop, one partner holds papers in their hand.

Post-pandemic retirement: Can we build more resilient systems?

A report by the Penn Wharton Budget Model finds that the Social Security Trust Fund in the U.S. would run out of money in 2032 or 2034—between two to four years earlier than pre-pandemic projections.

From Knowledge at Wharton

From coaching West Philly kids to the NBA
Taylor Jenkins

Taylor Jenkins. (Image: The Pennsylvania Gazette)

From coaching West Philly kids to the NBA

A student outreach project in West Philly and a timely internship helped launch Penn alum Taylor Jenkins’ NBA career as head coach of the Memphis Grizzlies.

The Pennsylvania Gazette

Anti-discrimination task force aims to ‘flatten the hate’
Gridded image with "flatten the hate" written across the front and the translation in various languages around the border

Penn's new task force supports Asian and Asian-American students, staff, and scholars. 

Anti-discrimination task force aims to ‘flatten the hate’

Launched in April, the new Task Force on Supporting Asian and Asian American students and scholars at Penn is offering events, seminars, and resources for countering and reporting stigma and anti-Asian behavior.

Kristina García

Interning virtually
Screenshot of a video call with 13 people

An open and engaging virtual orientation session set the tone for the Translational Research Internship Program, held online this year for the first time. (Image: Courtesy of Jessica German)

Interning virtually

The Translational Research Internship Program, offered by the Perelman School of Medicine’s Institute for Translational Medicine and Therapeutics Education Programs, provides mentorship for undergraduates as they complete a translational research project.

Katherine Unger Baillie