Cells that are starved of oxygen become dormant and grow acidic, halting protein synthesis. Reducing their acidity may be a key factor in improving cancer therapies.
Researchers at the Perelman School of Medicine found that dormant, acidic cells silence a molecular switch called mTORC, shutting down protein production and metabolic activity. In a study conducted on tumors grafted onto mice, baking soda that was added to the rodents’ drinking water “reawakened” dormant cells by reducing their acidity.
With dormant cells awakened, tumors may have a greater response to therapy. Previous research found a correlation between baking soda and immunotherapy, but lacked the details new research has found.
Read more at Penn Medicine News.