Through
11/26
Perelman School of Medicine
Paving a New Path to Parenthood: Penn Medicine Launches First Clinical Trial for Uterine Transplant in the Northeast
Penn Medicine will conduct the Northeast’s first clinical trial of uterine transplants, to provide women with Uterine Factor Infertility (UFI) - an irreversible form of female infertility that affects as many as 5 percent of women worldwide and 50,000 women in the United States - with a new path to parenthood.
Penn Study Pinpoints H3N2 Mutation in Last Year’s Flu Vaccine as Responsible for Lowered Efficacy
The low efficacy of last year’s influenza vaccine can be attributed to a mutation in the H3N2 strain of the virus, a new study reports.
Penn Medicine: Blood Flow in the Developing Heart Guides Maturation of Heart Valves
Congenital heart valve defects appear in 2 percent of all live births, making them the most common type of birth defect. While some of these defects have been linked to specific genetic mutations, the majority have no clearly definable genetic cause, suggesting that epigenetic factors – changes in gene expression versus an alteration in the genetic code -- play an important role.
Penn Study Links Mutations in Notch Gene to Role in B Cell Cancers
Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors, such as mantle cell lymphoma. However, the role of Notch in these cancers has been uncertain.
Moonshot Grant Will Help Researchers See Two of Cancer’s Key Food Sources at Once
Imagine trying to take a picture of a runner, but only being able to see her feet. If you could see her whole body, you’d get the full picture of how she uses both legs to put one foot in front of the other to reach top speed.
Penn Study Shows How Female Immune Cells Keep Their Second X Chromosome Shut Off
Autoimmune diseases tend to strike women more than men and having multiple X chromosomes could be the main reason why. While a process called X chromosome inactivation serves to balance out gene dosage between males and females, some genes on the “inactive X” chromosome in immune cells can sometimes escape this process, giving women an extra dose of immunity-related gene expression.
Seven Penn Faculty Members Elected to National Academy of Medicine
Seven University of Pennsylvania faculty members have been elected to the National Academy of Medicine (NAM), one of the nation’s highest honors in biomedicine. They are among 70 new U.S. and 10 international members of the globally renowned organization.
Researchers discover which brain region motivates behavior change
Have you ever been stuck in a rut, going through the same motions day in and day out? How do you motivate to change your behavior?
Penn-led Study Identifies Genes Responsible for Diversity of Human Skin Colors
Human populations feature a broad palette of skin tones. But until now, few genes have been shown to contribute to normal variation in skin color, and these had primarily been discovered through studies of European populations.
In the News
Philadelphia Inquirer
COVID patient who survived coma reunites with Penn care team
A COVID patient who survived his coma recently reunited with the Penn Medicine care team that helped save his life, including Jennifer Olenik of the Perelman School of Medicine.
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CNN
Vaping immediately affects vascular health and oxygen levels, study shows, even without nicotine
Research published by Marianne Nabbout while a resident at the Perelman School of Medicine finds that vaping has an immediate effect on blood vessels even if an e-cigarette doesn’t contain nicotine.
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Fox 29 (Philadelphia)
Former patient gives thanks to PA hospital staff after surviving coma, COVID-19 battle
A former COVID patient who spent six months in a coma returned to thank the Penn Medicine team that contributed to his survival, including Megan Carr-Lettieri.
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Philadelphia Inquirer
Is there a chemical link to memory loss? Penn researchers get $11M to study dementia causes
The National Institutes of Health have awarded $11 million to Aimin Chen of the Perelman School of Medicine to study the link between chemical exposures and dementia.
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Forbes
Insomnia may be more common than you think. Here’s what to know
According to Penn Medicine, about 1 in 4 Americans experiences difficulty with sleep each year.
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