4/22
Perelman School of Medicine
Penn/Vanderbilt Study: Genetic Risk Factors of Disparate Diseases Share Similar Biological Underpinnings
The discovery of shared biological properties among independent variants of DNA sequences offers the opportunity to broaden understanding of the biological basis of disease and identify new therapeutic targets, according to a collaboration between the Perelman School of Medicine at the University of Pennsylvania, the University of Arizona Health Sciences
Penn Institute for Biomedical Informatics and colleagues Identify "Roadmap" of Disease Mechanisms to Identify Candidate Drug Targets
The discovery of shared biological properties among independent variants of DNA sequences offers the opportunity to broaden understanding of the biological basis of disease and identify new therapeutic targets, according to a collaboration between the Perelman School of Medicine at the University of Pennsyl
Penn Study: A Long-noncoding RNA Regulates Repair of DNA Breaks in Triple-Negative Breast Cancer Cells
The discovery of long non-coding RNA (lncRNA) has dramatically changed the understanding of the biology of diseases such as cancer. The human genome contains about 20,000 protein-coding genes – less than 2 percent of the total – but 70 percent of the genome is made into non-gene-encoding RNA.
Penn Study: Medicare Patients Have Low Adherence to Biologic Drug Therapy for Psoriasis
About half of Medicare patients who start taking biologic therapies for moderate to severe plaque psoriasis stop within a year, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Previous studie
Penn Study Suggests Changes in Skin "Microbiome" During Canine Atopic Dermatitis Could Lead to Antibiotic-Free Therapies for Human and Canine Disease
Atopic dermatitis (AD), a chronic inflammatory skin condition and the most common form of eczema, is estimated to afflict as much as 10 percent of the U.S. population, and is much more common now than it was 50 years ago. Veterinary clinical estimates also show that approximately 10 percent of dogs have atopic dermatitis.
Cholesterol Levels, Not Statins, Influence Colorectal Cancer Risk, Penn Study Suggests
Long-term use of the cholesterol-lowering drugs known as statins does not appear to decrease a patient’s risk of colorectal cancer, suggests a new, large case-control study from Penn Medicine researchers published this week in&
Penn Study: Medicare Patients Have Low Adherence to Biologic Drug Therapy for Psoriasis
About half of Medicare patients who start taking biologic therapies for moderate to severe plaque psoriasis stop within a year, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Previous studie
Two Penn Medicine Physicians Elected to Association of American Physicians
Two Penn Medicine physicians – Ebbing Lautenbach, MD, MPH, MSCE, chief of the division of Infectious Diseases and the Robert Austrian Professor in the department of Medicine, and Ben Z.
Penn Study on Fragile X Syndrome Uses Fruitfly's Point of View to Identify New Treatment Paths
Fragile X syndrome (FXS) is the most common genetically inherited cause of intellectual disability in humans.
Penn Medicine Study Uncovers New Pathways that Control Skin Tanning and Lightening
When skin cells responsible for pigmentation are exposed to estrogen or progesterone, the cells respond by adjusting their melanin production, resulting in either skin darkening or lightening. Although pregnant women often experience alterations in skin pigmentation, the reason for the changes has long puzzled physicians.
In the News
How to die in good health
PIK Professor Ezekiel Emanuel says that incessantly preparing for old age mistakes a long life for a worthwhile one.
FULL STORY →
Mayor Parker’s plan to ‘remove the presence of drug users’ from Kensington raises new questions
Shoshana Aronowitz of the School of Nursing and Ashish Thakrar of the Perelman School of Medicine comment on the lack of specificity in Philadelphia’s plan to remove drug users from Kensington and on the current state of drug treatment in the city.
FULL STORY →
How many patients would recommend their Philly-area hospital to family and friends? Check your local hospital
The Hospital of the University of Pennsylvania has been named one of the most recommended acute-care facilities by patients in the Philadelphia area.
FULL STORY →
Homeward bound: When a Penn Medicine nurse was diagnosed with uterine cancer, she turned to the service dogs she helped to train
A profile highlights Maria Wright of Penn Medicine Lancaster General Health, from her volunteer work connecting people with service dogs to her cancer diagnosis and her own journey applying for a service dog.
FULL STORY →
Is apple cider vinegar really a cure-all?
Nitin K. Ahuja of the Perelman School of Medicine says there’s no supportive data that adding acid to the stomach will somehow help control acid reflux.
FULL STORY →