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A potential strategy to improve T cell therapy in solid tumors
Microscopic view of a DNA strand.

Image: Courtesy of Penn Medicine News

A potential strategy to improve T cell therapy in solid tumors

A new Penn Medicine preclinical study finds that a new simultaneous “knockout” of two inflammatory regulators boosted T cell expansion to attach solid tumors.

From Penn Medicine News

A moment for men’s health
A doctor and patient seated at a desk having a consultation.

Image: iStock/monkeybusinessimages

A moment for men’s health

Since 2012, the Basser Center for BRCA at Penn Medicine’s Abramson Cancer Center has been advancing lifesaving therapies and raising awareness of the risks faced by individuals with BRCA gene mutations.

Carter Johns

What drives transplant waitlisting disparities?
African American patient sitting on a hospital bed.

Image: iStock/Wavebreakmedia

What drives transplant waitlisting disparities?

For transplant patients, psychosocial evaluations, like other measures in the transplant process, can lead to people of color facing worse outcomes.

From Penn LDI

Can we intercept cancer?
A chart showing the intersection of a cell as it changes from pre-cancer to cancer stage one and two.

Image: Penn Medicine News

Can we intercept cancer?

Penn researchers are developing new ways to detect and “intercept” cancer from every angle, including basic science to understand the molecular changes that lead to cancer and developing new methods for finding it.

From Penn Medicine News

Genomics reveals a complex human history in Africa
Two people from the Hadza group pose and smile outdoors

Study participants included individuals from the Hadza, a group who traditionally practiced hunting and gathering and speak a language that includes click sounds. They live in what is now Tanzania.

(Image: Tishkoff Laboratory)

Genomics reveals a complex human history in Africa

An international team of researchers led by Penn geneticists sequenced the genomes of 180 Indigenous Africans. The results shed light on the origin of modern humans, African population history, and local adaptation.

Katherine Unger Baillie

World-renowned scientist Virginia Lee on her prominent career
Virginia Man-Yee Lee in her lab.

Virginia Man-Yee Lee, The John H. Ware 3rd Endowed Professor in Alzheimer’s Research at the Perelman School of Medicine and director of the Center for Neurodegenerative Disease Research.

(Image: Scott Spitzer)

World-renowned scientist Virginia Lee on her prominent career

Lee’s path to her groundbreaking discoveries stems from her unwavering dedication despite obstacles. Now, she looks forward to training the next generation of disease scientists at Penn.

From Penn Memory Center

New insights into the mechanisms of tumor growth
3d render of cells secreting exosomes.

Nocred

New insights into the mechanisms of tumor growth

A team of researchers led by the School of Arts & Science’s Wei Guo characterize the molecular pathways that play a major role in tumorigenesis, findings that could lead to better diagnostic tools for cancer and new targeted therapies.
From a small town in Lebanon to cancer research
A banner hanging outside in a small town in Lebanon.

Image: Courtesy of Penn Medicine News

From a small town in Lebanon to cancer research

When Mayassa Bou-Dargham, a postdoctoral fellow in Penn’s Abramson Family Cancer Research Institute received a pilot project grant, a banner was hung in her Lebanese hometown. Getting there took years of determination, self-confidence and, in small part, fate.

From Penn Medicine News

Three ways to respond following the earthquake in Turkey and Syria
A building standing amid piles of rubble set against a blue sky. The building is partially collapsed.

A building in Antakya, in southeastern Turkey, was heavily damaged during the earthquake in Turkey and Syria.

(Image: AP Photo/Bernat Armangue)

Three ways to respond following the earthquake in Turkey and Syria

Guidance from the Center for High Impact Philanthropy, Penn Global, and Penn Medicine’s disaster preparedness team on how to help from afar and what resources are available on campus.

Michele W. Berger, Kristina García , Juliana Rosati