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How HIV infection shrinks the brain’s white matter
Fluorescent microscopic image of a brain cell stained in blue and yellow

How HIV infection shrinks the brain’s white matter

Researchers from Penn and CHOP detail the mechanism by which HIV infection blocks the maturation process of brain cells that produce myelin, a fatty substance that insulates neurons.

Katherine Unger Baillie

Researchers discover drug that blocks multiple SARS-CoV-2 variants
Microscopic view of lung epithelial cells.

Lung epithelial cells infected with SARS-CoV-2 (left, yellow) were successfully treated with the STING agonist diABZI (right) by Penn Medicine researchers. (Image: Penn Medicine News)

Researchers discover drug that blocks multiple SARS-CoV-2 variants

The drug diABZI—which activates the body’s innate immune response—was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2 and likely other coronaviruses.

Lauren Ingeno

Honing cultural humility skills can improve health care as a whole
Cartoon of medical professionals standing one-on-one with individuals of various races, ages, family structure.

Honing cultural humility skills can improve health care as a whole

At Penn Medicine, medical personnel are adopting cultural humility as an ongoing process of developing a set of skills to approach any individual from any culture at any time.

From Penn Medicine News

Hepatitis C screening doubles when tests ordered ahead of time
hep c lab paperwork and sample vials next to a computer keyboard.

Hepatitis C screening doubles when tests ordered ahead of time

By sending eligible patients a screening order along with the usual reminder, Penn Medicine researchers show they could double hepatitis C screening rates.

From Penn Medicine News

A mental health checkup for children and adolescents, a year into COVID
A young person wearing a mask and polka dot t-shirt leaning against a faux wooden wall.

A mental health checkup for children and adolescents, a year into COVID

As a whole, this group experienced a significant short-term psychological toll. Though the long-term consequences aren’t yet known, particularly given how the year disproportionately exacerbated adverse childhood experiences, Penn experts remain cautiously optimistic.

Michele W. Berger

Neuro-oncologist joins Penn’s mission to fight brain cancer
Richard Phillips in a white lab coat.

Richard E. Phillips, a Presidential Assistant Professor of Neurology and member of the Penn Epigenetics Institute. (Image: Courtesy of Penn Medicine)

Neuro-oncologist joins Penn’s mission to fight brain cancer

Richard Phillips, a Presidential Assistant Professor of Neurology and member of the Penn Epigenetics Institute, hopes to bring glioma research out of the “basement.”
The potential role of vaccine certificates in the next phase of the pandemic
a person wearing a mask with a QR code on their phone scanning their ticket in an airport

The potential role of vaccine certificates in the next phase of the pandemic

Public health law expert Eric Feldman and medical ethicist Emily Largent discuss the legal and ethical implications of companies and organizations requiring proof of vaccination to reengage with different sectors of the economy.

Erica K. Brockmeier