Borrowing nature’s blueprint: How scientists replicated bone marrow The new chip will allow for automated experiments, and can be connected to chip-based models of other organ systems, like the lungs.(Image: Dan Huh) Borrowing nature’s blueprint: How scientists replicated bone marrow A collaborative research team from Penn Engineering, Penn Medicine, and the Children’s Hospital of Philadelphia have developed a chip that mimics human bone marrow.
BEND lipids improve LNP mRNA delivery and gene editing A sample of the new lipids, which improve the success rate of lipid nanoparticles delivering their contents.(Image: Sylvia Zhang) BEND lipids improve LNP mRNA delivery and gene editing Penn Engineering researchers have developed a new class of lipids called branched endosomal disruptor (BEND) lipids to better deliver mRNA and gene-editing tools.
Who to vaccinate first? Answering a life-or-death question with network theory Image: iStock/manassanant pamai Who to vaccinate first? Answering a life-or-death question with network theory Researchers from Penn Engineering and Penn Medicine have collaborated to determine the best theoretical strategy for a vaccine rollout.
Beth A. Winkelstein reappointed as deputy provost Deputy Provost Beth A. Winkelstein.(Image: Kevin Monko) Beth A. Winkelstein reappointed as deputy provost Winkelstein has taught at Penn for more than twenty years as a leader of interdisciplinary research, and has served as deputy provost since 2020.
Revolutionizing data centers: Penn Engineers’ breakthrough in photonic switching Image: Bella Ciervo Revolutionizing data centers: Penn Engineers’ breakthrough in photonic switching Researchers have developed a photonic switch that can redirect signals in trillionths of a second with minimal power consumption.
New ways to modulate cell activity remotely Cells are dynamic, fast-changing, complex, tiny, and often hard-to-see in environments that don’t always behave in predictable ways when exposed to external stimuli. Now, researchers led by Lukasz Bugaj of the School of Engineering and Applied Science have found new ways to modulate cell activity remotely.(Image: iStock/Maksim Tkachenko) New ways to modulate cell activity remotely Penn researchers use temperature to guide cellular behavior, promising better diagnostics and targeted therapies.
New quantum sensing technology reveals subatomic signals A rendering of the minute nucleic differences detectable using the form of nuclear quadrupolar resonance.(Image: Mathieu Ouellet) New quantum sensing technology reveals subatomic signals Penn Engineers have created a novel approach to detect tiny variations in individual atoms, enabling protein research in drug development.
Breakthroughs in gene editing and expression control with mvGPT Sherry Gao, Tyler Daniel (pictured), and their coauthors have developed a new tool that can simultaneously and independently edit multiple genes and regulate their expression.(Image: Bella Ciervo) Breakthroughs in gene editing and expression control with mvGPT Penn Engineers have created a gene editing tool that can address different genetic diseases in the same cell.
Violent language in film has increased Violent language in film has increased A new study from the Annenberg School for Communication finds that violent speech in movies is increasing over time, even in non-crime films. 1 min. read
Penn Center for Innovation celebrates 10 years (Image: Eric Sucar) Penn Center for Innovation celebrates 10 years The University’s nexus for technology transfer supports researchers in their innovative efforts, from CAR T to mRNA advancements that have dramatically reshaped the world.