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School of Veterinary Medicine
A Perturbed Skin Microbiome Can Be ‘Contagious’ and Promote Inflammation, Penn Study Finds
Even in healthy individuals, the skin plays host to a menagerie of bacteria, fungi and viruses. Growing scientific evidence suggests that this lively community, collectively known as the skin microbiome, serves an important role in healing, allergies, inflammatory responses and protection from infection.
Fossil ‘Winged Serpent’ Is a New Species of Ancient Snake, Penn Doctoral Student Finds
An ancient sink hole in eastern Tennessee holds the clues to an important transitional time in the evolutionary history of snakes. Among the fossilized creatures found there, according to a new paper co-authored by a University of Pennsylvania paleontologist, is a new species of snake that lived 5 million years ago.
Penn Team Characterizes the Underlying Cause of a Form of Macular Degeneration
Named for Friedrich Best, who characterized the disease in 1905, Best disease, also known as vitelliform macular dystrophy, affects children and young adults and can cause severe declines in central vision as patients age. The disease is one in a group of conditions known as bestrophinopathies, all linked to mutations in the BEST1 gene.
Look to Lactate to Help Predict Ill Cats’ Prognoses, Penn Vet Study Says
Many factors go into evaluating the prognosis of a critically ill animal, usually involving a combination of objective metrics, such as blood pressure or blood oxygenation, and more subjective clinical signs, such as alertness or lethargy.
Penn Vet Library Exhibit Explores the Human-Animal Connection Through Art
Eleanor Hubbard, an artist and University of Pennsylvania alumna, is a firm believer in the power of serendipity. Without it, her latest exhibition, “Natural Selection: Lost Cat, Found Ox and Other Inspiring Bonds,” would have never come to be.
Mathematical Models Lend Penn Vet Professor Insights Into Diabetes
For a trove of examples of the rich outcomes of interdisciplinary work, look no further than Darko Stefanovski’s research portfolio.
Penn Vet Team Identifies New Therapeutic Targets for the Tropical Disease Leishmaniasis
Each year, about 2 million people contract leishmaniasis, a parasitic disease transmitted by the bite of a sand fly. The cutaneous form of the disease results in disfiguring skin ulcers that may take months or years to heal and in rare cases can become metastatic, causing major tissue damage.
T Cells Support Long-lived Antibody-producing Cells, Penn-led Team Finds
If you’ve ever wondered how a vaccine given decades ago can still protect against infection, you have your plasma cells to thank. Plasma cells are long-lived B cells that reside in the bone marrow and churn out antibodies against previously encountered vaccines or pathogens.
Penn Vet Study Shows How Solid Tumors Resist Immunotherapy
Immunotherapies have revolutionized cancer treatment, offering hope to those whose malignancies have stubbornly survived other existing treatments. Yet solid tumor cancers are often resistant to these approaches.
Penn Vet Research Identifies New Target for Taming Ebola
Viruses and their hosts are in a eternal game of one-upmanship. If a host cell evolves a way to stop a virus from spreading, the virus will look for a new path. And so on and so forth.
In the News
San Francisco Chronicle
Fentanyl overdoses hit a surprising group of San Franciscans: the city’s dogs
Cynthia Otto of the School of Veterinary Medicine says that fentanyl can be absorbed across the mucous membranes in canine noses, causing dogs to face a life-threatening overdose.
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The Washington Post
How to (responsibly) let your cat outside
James Serpell of the School of Veterinary Medicine says that some cats are perfectly happy within the confines of the home, while others have a greater desire to wander, explore, and investigate.
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The Washington Post
Cats aren’t jerks. They’re just misunderstood
James Serpell of the School of Veterinary Medicine says that the domestic cat suffers from its legacy of being a not-quite-wild animal on the margins of society.
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Newsweek
Dog respiratory illness map update: Mystery disease spreads to more states
Deborah Silverstein of the School of Veterinary Medicine says that the dogs most at risk for respiratory illness are those with low immunity, such as young puppies, the unvaccinated, or older dogs, and potentially short-nosed breeds.
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NBC News
What’s causing severe respiratory illnesses in dogs?
Deborah Silverstein of the School of Veterinary Medicine says that more dogs may be getting severely ill because they have been infected with multiple pathogens at the same time.
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