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Who, What, Why: John Donges
John Donges sitting on a bench in an outside courtyard

John Donges, Penn Vet associate director of marketing, has just completed the 100th issue of the School's Bellwether magazine as guest editor. 

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  • Who, What, Why

    • Who, What, Why: John Donges

    At Penn Vet for more than two decades, John Donges has worked on nearly half the issues of Bellwether, the School’s alumni and donor magazine. So, it made sense that he was the editor of a special 100th issue, publishing this month.
    Uncovering the role of skin microbiome and immune response in cutaneous leishmaniasis
    Five people standing in a lab.

    Researchers at Penn’s School of Veterinary Medicine and the Perelman School of Medicine studying leishmaniasis are leading the way to potential new therapies. From left, Camila Amorim, Phillip Scott, Elizabeth A. Grice, Daniel P. Beiting, and Tej Singh.

    Image: John Donges for Penn’s School of Veterinary Medicine.

    Uncovering the role of skin microbiome and immune response in cutaneous leishmaniasis

    Two new studies led by Phillip Scott of the School of Veterinary Medicine and Elizabeth Grice of the Perelman School of Medicine demonstrate how bacteria found in leishmaniasis skin lesions and an associated immune response drive disease burden and treatment failure—and suggest new possibilities for treatment of the parasitic disease.

    Abbey Porter

    Study shows promise for iNKT cell platform to treat cancer
    Canine iNKT cells.

    Canine iNKT cells

    (Image: Courtesy of Nicola Mason and Antonia Rotolo)

    Study shows promise for iNKT cell platform to treat cancer

    Researchers from the School of Veterinary Medicine and Perelman School of Medicine have shown that invariant natural killer T cells from a healthy donor can persist in MHC-mismatched canines, demonstrating a reliable platform to inform human clinical trials.
    Measuring the ripple effects of reforestation and sustainable cocoa cultivation
    cocoa beans

    (Image: Christina Seybolt, courtesy of Heather Huntington)

    Measuring the ripple effects of reforestation and sustainable cocoa cultivation

    With support from the Penn Global Engagement Fund, Heather Huntington is investigating the impact of reforestation and sustainable agriculture interventions on livelihoods, biodiversity, and human health in Ghana and Côte d’Ivoire.

    Liana F. Wait

    Deans of health schools discuss climate change in their fields
    Deans sit on Climate Week panel.

    Kathy D. Morrison, faculty lead for the Environmental Innovations Initiative; Andrew M. Hoffman, dean of the School of Veterinary Medicine; Antonia M. Villarruel, dean of the School of Nursing; Farah Hussain, representing the dean of the Perelman School of Medicine; Sara S. Bachman, dean of School of Social Policy and Practice; Mark Wolff, dean of the School of Dental Medicine; and Julian Fisher, director of Oral and Planetary Health Policies in Penn Dental, sit onstage for a Climate Week discussion on climate and health.

    (Image: Tommy Leonardi)

    Deans of health schools discuss climate change in their fields

    Deans and leaders from the schools of Medicine, Veterinary Medicine, Dental Medicine, Nursing, and Social Policy & Practice discussed climate and health at a Climate Week event.
    Removing the barrier surrounding solid tumors clears path for T cells
    Stroma-targeting CAR T cells (green) in the stroma surrounding a solid tumor.

    Stroma-targeting CAR T cells (green) accumulate in the stroma surrounding a tumor in a mouse model of pancreatic cancer.

    (Image: Zebin Xiao)

    Removing the barrier surrounding solid tumors clears path for T cells

    Penn researchers uncover a new way to target solid tumors. Using CAR T cells to remove cancer-associated fibroblasts surrounding pancreatic tumors allows T cells to infiltrate and attack the tumor cells.

    Liana F. Wait

    Genetic switch turns tumor suppressor into oncogene in colorectal cancer
    Fluorescent microscopy of colon cancer cells..

    (Image: Yuhua Tian)

    Genetic switch turns tumor suppressor into oncogene in colorectal cancer

    Researchers from the School of Veterinary Medicine have shown that an enzyme that suppresses early-stage colorectal cancer switches to become an oncogene as the cancer progresses.

    Liana F. Wait

    Social ecology and community work in the Galápagos
    students studying the galapagos, sitting on waterfront

    (On homepage) On a Penn Global Research Institutes outing to Tortuga Bay, students and Penn Global’s Laurie Jensen sit on rocks in a lava field overlooking a hypersaline pool.

    (Image: Michael Weisberg)

    Social ecology and community work in the Galápagos

    Undergraduate and graduate students spent two months on San Cristóbal Island this summer, doing research on antibacterial resistance, vectors of disease, climate change adaptation, and the impact of climate change on mental health.
    Penn Vet students helping animals and their owners in Thailand
    Allison Oakes examining a cat.

    Allison Oakes examines a cat at the Bangkok clinic.

    (Image: Claire Clemens)

    Penn Vet students helping animals and their owners in Thailand

    This summer, 14 students from the School of Veterinary Medicine traveled to Thailand to spay and neuter cats and dogs for owners who would otherwise be unable to afford the procedures.

    Liana F. Wait

    Could we breed cows that emit less methane?
    Dipti Pitta kneeling next to a Holstein dairy cow.

    Penn Vet’s Dipti Pitta is investigating whether it’s possible to selectively breed dairy cows to have more efficient microbiomes.

    (Image: Chris Boyle) 

    Could we breed cows that emit less methane?

    In a new study, researchers from the School of Veterinary Medicine identified attributes of low-methane-emitting dairy cows that could be used as targets for selective breeding.

    Liana F. Wait