CAR T cell therapy may eliminate tumor cells missed by surgery CAR T cell therapy may eliminate tumor cells missed by surgery The results of a study led by Penn Medicine’s Carl June greenlights preclinical trials for the application of CAR T therapy in gel form to surgical wounds following partial tumor removal to eliminate residual tumor cells.
The Jin Lab taps into a key cell for cancer research The lab, led by Chengcheng Jin, an assistant professor of cancer biology and microbiology, is investigating how the immune system co-evolves with tumors during cancer progression. (Image: Penn Medicine News) The Jin Lab taps into a key cell for cancer research The lab, led by Chengcheng Jin, an assistant professor of cancer biology and microbiology, is investigating how the immune system co-evolves with tumors during cancer progression.
FDA approves ‘glowing tumor’ imaging drug to aid lung cancer surgery FDA approves ‘glowing tumor’ imaging drug to aid lung cancer surgery The injectable diagnostic, Cytalux, binds to cancerous tissue and glows, making it easier for surgeons to remove tumors completely while sparing healthy tissue.
Advances in cancer research Interleukin-18 is a protein which in humans is encoded by the IL18 gene. “We designed an ‘armored’ CAR that secretes IL18 where we found it to have potent antitumor efficacy in our preclinical studies,” said Carl June. (Image: Penn Medicine News) Advances in cancer research Recent research shows promise in a novel CAR T therapy after cancer relapse, and a novel treatment for multiple myeloma.
How the perception of risks and benefits influence cancer clinical trial withdrawal outcomes How the perception of risks and benefits influence cancer clinical trial withdrawal outcomes A new study from the School of Nursing examines the association between patients’ perceived benefits and burdens of research participation and withdrawal.
Another Crispr first: New treatment wipes out teen’s cancer Penn In the News The Washington Post Another Crispr first: New treatment wipes out teen’s cancer Bruce Levine of the Perelman School of Medicine says that the latest results of Crispr gene editing in a cancer patient have showcased the best possible clinical outcome thus far. CRISPR gene-editing may boost cancer immunotherapy, new study finds Penn In the News NPR CRISPR gene-editing may boost cancer immunotherapy, new study finds Carl June of the Perelman School of Medicine says that off-the-shelf CAR-T cell therapies using CRISPR would be a game-changer. Study shows promise of new anti-KRAS drug for pancreatic cancer Study shows promise of new anti-KRAS drug for pancreatic cancer A small molecule inhibitor that attacks the difficult cancer-causing gene mutation KRAS successfully shrunk tumors or stopped cancer growth in preclinical models of pancreatic cancer. HPV-related cancers are on the rise in men HPV-related cancers are on the rise in men Recent CDC data show that roughly four of every 10 cases of HPV-induced cancer now occur in men. Penn Medicine research has found that differences in levels of a particular HPV protein may inform treatment. CAR T cell therapy reaches beyond cancer CAR T cell therapy reaches beyond cancer Penn Medicine researchers laud the early results for CAR T therapy in lupus patients, which point to broader horizons for the use of personalized cellular therapies. Load More
CRISPR gene-editing may boost cancer immunotherapy, new study finds Penn In the News NPR CRISPR gene-editing may boost cancer immunotherapy, new study finds Carl June of the Perelman School of Medicine says that off-the-shelf CAR-T cell therapies using CRISPR would be a game-changer. Study shows promise of new anti-KRAS drug for pancreatic cancer Study shows promise of new anti-KRAS drug for pancreatic cancer A small molecule inhibitor that attacks the difficult cancer-causing gene mutation KRAS successfully shrunk tumors or stopped cancer growth in preclinical models of pancreatic cancer. HPV-related cancers are on the rise in men HPV-related cancers are on the rise in men Recent CDC data show that roughly four of every 10 cases of HPV-induced cancer now occur in men. Penn Medicine research has found that differences in levels of a particular HPV protein may inform treatment. CAR T cell therapy reaches beyond cancer CAR T cell therapy reaches beyond cancer Penn Medicine researchers laud the early results for CAR T therapy in lupus patients, which point to broader horizons for the use of personalized cellular therapies.
Study shows promise of new anti-KRAS drug for pancreatic cancer Study shows promise of new anti-KRAS drug for pancreatic cancer A small molecule inhibitor that attacks the difficult cancer-causing gene mutation KRAS successfully shrunk tumors or stopped cancer growth in preclinical models of pancreatic cancer.
HPV-related cancers are on the rise in men HPV-related cancers are on the rise in men Recent CDC data show that roughly four of every 10 cases of HPV-induced cancer now occur in men. Penn Medicine research has found that differences in levels of a particular HPV protein may inform treatment.
CAR T cell therapy reaches beyond cancer CAR T cell therapy reaches beyond cancer Penn Medicine researchers laud the early results for CAR T therapy in lupus patients, which point to broader horizons for the use of personalized cellular therapies.