Genetics

Philadelphia Inquirer

These eight diseases are so rare that drug firms haven’t tried treating them with gene therapy. A $97 million program aims to help

Gene therapy for a rare form of blindness will be tested at Penn Medicine while gene therapy for a condition that causes skeletal deformities and seizures will be tested at the Children’s Hospital of Philadelphia.

Microscopic rendering of mRNA gene editing.

‘In vivo’ RNA-based gene editing model for blood disorders developed

Researchers from Penn Medicine and The Children’s Hospital of Philadelphia show that gene editing tools can be delivered via lipid nanoparticles, which would reduce cost and increase access to cutting-edge gene therapies.

National Geographic

Could eating like our ancestors make us healthier?

PIK Professor Sarah Tishkoff says that humans have continued to evolve since the Paleolithic period.

Nature.com

Developing human embryos imaged at highest-ever resolution

Nicolas Plachta of the Perelman School of Medicine comments on a new technique that allows researchers to study crucial events in the first few days of development without genetically altering the embryos.

Katalin Susztak hunts for a cure for kidney disease

Throughout her career, the professor of internal medicine, nephrology, and genetics has had a profound impact on the way kidney disease is identified, prevented, and managed.

Indo-Asian News Service

How our genes make us prone to allergies

A team of researchers from the Perelman School of Medicine found that small changes in the protein called ETS1 can lead to an increased likelihood of allergic reactions that cause inflammation.

person scratching their arm with their other hand

A better understanding into how genes make us prone to allergies

Slight alterations in the ETS1 protein level can lead to allergic inflammation.

NPR

His baby gene editing shocked ethicists. Now he’s in the lab again

Kiran Musunuru of the Perelman School of Medicine says that Chinese geneticist He Jiankui crossed ethical lines and exhibited bad science by editing babies’ genes.

Stat

Academia’s postdoc system is teetering, imperiling efforts to diversify life sciences

As co-chair of an NIH group to re-envision postdoctoral training, PIK Professor Shelley Berger expresses concern about the future of academic research.

A man sits with a doctor holding an iPad.

Three things to know about BRCA mutations in men

Kara Maxwell, director of the Men & BRCA Program at the Basser Center, is bridging the knowledge gap about how BRCA mutations affect men.

Filters