Immunology | Penn Today

An mRNA vaccine against Lyme disease-causing bacteria

In pre-clinical models, researchers at Penn Medicine have developed a vaccine that protects against Borrelia burgdorferi, the bacteria that causes Lyme disease.

Four bottles of Influenza vaccine beside one medical syringe.

Q&A

This season’s flu and COVID-19 vaccines

Judith A. O’Donnell of the Perelman School of Medicine answers common questions about this year’s flu shot and the new COVID-19 vaccines.

The immune health future, today

Breaking the code of the immune system could provide a new fundamental way of understanding, treating, and preventing every type of disease. Penn Medicine is investing in key discoveries about immunity and immune system function, and building infrastructure, to make that bold idea a reality.

Stroma-targeting CAR T cells (green) in the stroma surrounding a solid tumor.

Removing the barrier surrounding solid tumors clears path for T cells

Penn researchers uncover a new way to target solid tumors. Using CAR T cells to remove cancer-associated fibroblasts surrounding pancreatic tumors allows T cells to infiltrate and attack the tumor cells.

Penn’s cell therapy pioneer Dr. Carl June shares $3M Breakthrough Prize in Life Sciences

Carl June of the Perelman School of Medicine has been awarded a $3 million Breakthrough Prize in life sciences for developing CAR-T therapy to treat cancer, with remarks from President Liz Magill.

Penn Medicine’s Carl June to receive 2024 Breakthrough Prize in Life Sciences

The Richard W. Vague Professor in Immunotherapy in the Perelman School of Medicine is honored for pioneering the development of CAR T cell therapy, which programs patients’ own immune cells to fight their cancer.

Penn’s Carl June splits a $3 million Breakthrough Prize for pioneering the cancer treatment CAR-T

Carl June of the Perelman School of Medicine has been honored with the $3 million Breakthrough Prize for discovering how to attack cancer by harnessing a patient’s immune system through CAR-T therapy.

Penn biomedical scientists move into new uCity complex with 115,000 square feet of lab space

More than 50 Penn scientists and staff, including the Perelman School of Medicine’s Drew Weissman, are moving into 115,000 square feet of new lab space in the 13-story One uCity Square building.

Cancer treatment has come far, fast: Better prevention, early detection, new treatment

Carl June of the Perelman School of Medicine was awarded a $3 million Breakthrough Prize in life sciences for developing CAR-T therapy to treat cancer.

3d render of T cells attacking cancer cells

A suit of armor for cancer-fighting cells

New research from the University of Pennsylvania offers a safer path for CAR T cell immunotherapy.

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