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A successful lipid nanoparticles drug delivery system targets notoriously hard-to-target activated fibroblasts in the liver.
Penn Engineers are working to make controlling microscopic processes, such as transporting drugs to tumors for precise therapies, faster, safer, and more reliable through the use of microrobots.
A team of researchers from the School of Engineering and Applied Science has introduced a computing architecture ideal for AI using an approach known as compute-in-memory.
Technology developed by Arnold Mathijssen of the School of Arts & Sciences and colleagues could one day clear blockages in blood vessels or precisely target chemotherapy drugs to a tumor.
Chemical separation processes are essential to manufacturing, but also consume high levels of energy. Penn Engineers are developing new membranes for energy-efficient membrane-based separations on a nanoscale level.
Recent research demonstrates how a new class of polymers can produce small, precise patterns on the nanometer scale, with future implications for large-scale computer chip fabrication.
Penn Medicine researchers have developed a new technique that uses complement inhibitor Factor I to prevent proteins from attacking treatment-carrying nanoparticles so they can better reach targets within the body.
With an NSF grant, Penn Engineering researchers are developing a new manufacturing technique that would be able to produce mRNA sequences in a way that removes the need for cryogenic temperatures.
With a “liquid assembly line,” Penn researchers have produced mRNA-delivering-nanoparticles significantly faster than standard microfluidic technologies.
The competitive program, managed by Office of the Vice Provost for Research, is designed to support early career researchers and scholars while enriching the Penn community.
Mark Miskin of the School of Engineering and Applied Science is using tools from the semiconductor industry to develop nanotechnologies for microscopic robots.
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In collaboration with the University of Ljubljana, Kathleen Stebe of the School of Engineering and Applied Science has built a swimming microrobot that paddles by rotating liquid crystal molecules.
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Hun Michel Koo of the School of Dental Medicine, Edward Steager of the School of Engineering and Applied Science, and colleagues have created automated shapeshifting microrobots with the ability to brush, floss, and rinse teeth.
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Capstan Therapeutics, a Penn spinout whose founders include Carl June, Bruce Levine, and Drew Weissman of the Perelman School of Medicine, has launched with $165 million raised to develop a new type of CAR therapy that incorporates mRNA.
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Charles Kane and Eugene Mele of the School of Arts and Sciences have been honored with the John Scott Award, given annually to innovators in science, for their work developing ways to predict the behavior of atomic particles.
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