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Gut cells sound the alarm when parasites invade
Black and white microscopic image of many cells clustered tightly

The parasite Cryptosporidium, transmitted through water sources, is one of the most common causes of diarrheal disease in the world. (Image: Muthgapatti Kandasamy and Boris Striepen)

Gut cells sound the alarm when parasites invade

A chain reaction led by cells lining the intestines tips the immune system off to the presence of the parasite Cryptosporidium, according to a study led by researchers in the School of Veterinary Medicine.

Katherine Unger Baillie

From PPE to lab safety, supporting the campus community is a full-time job
a person at the far end of a lab working on a computer

From PPE to lab safety, supporting the campus community is a full-time job

The Environmental Health and Radiation Safety office plays an important role in keeping Penn safe and healthy. Now, during the COVID-19 crisis, the office has stepped up to support the resumption of on-campus activities.

Erica K. Brockmeier

Project Quaker testing program key to a safe campus reopening
a person looking at a robotic pipetting machine on the other side of a glass partition

Project Quaker testing program key to a safe campus reopening

Developed in partnership with Penn Medicine, the program aims to conduct 40,000 COVID-19 tests each week and will support ongoing plans to bring students back to campus this spring.

Erica K. Brockmeier

Translating groundbreaking scientific discoveries into practical technologies
a cartoon of four researchers one with a notebook, one looking through a microscope, one injecting liquid into a test tube, and one looking at two flasks

Translating groundbreaking scientific discoveries into practical technologies

Amidst the numerous challenges posed by COVID-19, the Penn Center for Innovation has continued to facilitate impactful innovations created at Penn, fostering partnerships and helping to realize new products and businesses.

Erica K. Brockmeier

One step closer to a clinical fix for the side effects of monovision
A person sitting in front of a computer and a machine that tests vision.

The lab of neuroscientist Johannes Burge (above) focuses on how the human visual system processes the images that fall on the back of the eye. This line of work, closely related to a 100-year-old illusion called the Pulfrich effect, could have serious public safety and public health implications.

One step closer to a clinical fix for the side effects of monovision

Monovision counters the deterioration of the ability to see up close but also causes dramatic visual distortions. New research confirms that a solution that successfully works with trial lenses—the special lenses used by eye doctors—also succeeds with contact lenses.

Michele W. Berger

Uniting against an invisible foe
microscopic image of covid-19

A tiny virus has transformed life as we know it. But in nearly every corner of Penn’s campus, researchers are making remarkable progress to combat it.

(Image, also on homepage: National Institutes of Health)

Uniting against an invisible foe

All across the University, researchers have launched new areas of study, reaching across disciplinary boundaries to make stunning progress in combating COVID-19.

Katherine Unger Baillie

Parasitic worms offer ‘the missing link’ on the dual nature of a key immune regulator
Microscopic image of cell labeled with red, blue, and green

Samples of nasal polyps removed from patients with chronic rhinosinusitis revealed the perforin-2 protein (labeled in green) in the cellular plasma membrane. A pore protein, perforin-2 may be how IL-33, a key immune signaling molecule, is able to exit these cells to trigger an immune response, according to new work led by a Penn Vet-led team. (Image: Courtesy of De’Broski Herbert)

Parasitic worms offer ‘the missing link’ on the dual nature of a key immune regulator

Whether the signaling molecule IL-33 wakes up or turns down the immune response depends on what cell type releases it, School of Veterinary Medicine researchers found.

Katherine Unger Baillie

Wellness resources at your fingertips
Person performs a yoga pose in a home

Wellness resources at your fingertips

When facing the challenges of the current moment, Penn students, faculty, and staff have options to promote their emotional, mental, and physical well-being.

Katherine Unger Baillie