12.8
Health Sciences
Hospitals prepare for future disasters to prevent shortages of life-saving drugs
Fallout from previous hurricanes has made hospital staff more aware of the risks natural disasters bring, and are proactive in anticipating drug shortages and supplies.
Targeting a viral vulnerability to treat disease
Robert Ricciardi company ViRAZE utilizes interdisciplinary approaches to drug discovery. Its first target is molluscum contagiosum, a disease that targets children and immune-compromised adults with no current FDA-approved therapy.
Flu vaccination rates in clinics drop as day progresses, but ‘nudges’ give them a boost
A new study shows that nudges prompting staff to create templates for vaccine orders increases flu vaccination rates.
Regrowing dental tissue with stem cells from baby teeth
In a clinical trial led by Songtao Shi of the School of Dental Medicine, stem cells extracted from baby teeth were used to regrow the living tissue in teeth damaged by injury. The promising findings highlight the potential of dental stem cells, which could be used in a wide range of dental procedures, or treating certain systemic diseases.
New center will study the complex genomics within individual cells
Junhyong Kim and James Eberwine are leading a multi-disciplinary team in developing cutting-edge technologies that can assess the genetic material inside individual compartments of single cells. The new Center for Sub-Cellular Genomics aims to revolutionize therapies for diseases such as bipolar disorder, autism, and Alzheimer’s disease.
Analyzing roadside dust to identify potential health concerns
Reto Gieré is working with collaborators across the world to identify an overlooked but significant factor in traffic-related air pollution: Tiny bits of tires, brake pads, and road materials that become suspended in the air when vehicles pass over.
Finding patterns in a class of neurological disorders
Research from Penn Engineering and the Perelman School of Medicine has found that the shared pattern is misfolded in Fragile X Syndrome, a member of the class of disorders that also includes ALS and Huntington’s disease
Stigmatizing views and myths about psoriasis are pervasive
New multidisciplinary research involving both psychologists and dermatologists from the Perelman School of Medicine is the first to examine how common this stigma may be among the general population of the United States.
An oasis of compassion
Since 2015, the Hospital of the University of Pennsylvania has supported the Family Caregiver Center, a three-room space that serves an array of needs, from resources to relaxation, for caregivers—one of only a few in the United States.
CAR T cell therapy receives approval for use across European Union
The European Commission has approved a personalized cellular therapy developed at the Abramson Cancer Center, making it the first CAR T cell therapy permitted for use in the European Union in two distinct indications.
In the News
Science
What now for human genome editing?
The Perelman School of Medicine’s James Wilson discussed possible venues for the scientific oversight of controversial research. The FDA could be a good option, he suggested, but the organization would have to change its confidentiality restrictions to supervise effectively.
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Reader’s Digest
The 10 most common types of cancer in the United States
Thomas Karasic of the Perelman School of Medicine weighed in on treatments for liver and pancreatic cancers.
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Today
Died of a broken heart? The science behind close couple deaths
David Casarett of the Perelman School of Medicine spoke about the phenomenon of spouses dying shortly after one another. Casarett said social and cultural factors may play a role, as in cases when “the surviving spouses stop taking care of themselves. Sometimes they become depressed.”
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Philadelphia Inquirer
Black and Hispanic Americans have a harder time quitting cigarettes. Will this Penn study find a way to help?
Researchers from the Perelman School of Medicine, led by Scott Halpern, are exploring better ways to support smoking cessation in black and Latino populations. “We’re confident that if we succeed in producing this evidence, health systems and payers will respond,” Halpern said.
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Smithsonian Magazine
What’s new, and what’s not, in the reported birth of the CRISPR babies
The Perelman School of Medicine’s Kiran Musunuru said that the birth of gene-edited babies does not constitute a scientific advancement because “there was nothing preventing previous researchers who edited human embryos from doing the same, except their own ethics and morals.”
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