Health Sciences

Clarifying T cell ‘exhaustion’

T cells, which are among the most powerful weapons in the immune systems of humans and other vertebrates, remain substantially programmed to stay exhausted even many weeks after exposure to a virus ended.

Hannah Messinger

100 years of insulin

On July 27, 1921, Canadian doctors Frederick Banting and Charles Best successfully isolated the hormone insulin, one of the most important breakthroughs in treating diabetes. Experts from around the University share their thoughts on the medical triumph on the 100th anniversary.

Kristen de Groot

In the News

The New York Times

Managing ADHD is hard. These coaches want to help

Lisa Joy Tutttle of the Perelman School of Medicine spoke about Penn’s Adult A.D.H.D. Treatment and Research Program, which provides clients with coaching and other support. “We’re really trying to help people develop their own insights and solutions,” she said.


Philadelphia Business Journal

Cell therapy pioneer Dr. Carl June to chair Chinese biotech firm's scientific advisory board

Carl June of the Perelman School of Medicine has agreed to serve as chairman of Bioheng Biotech Co.’s scientific advisory board. "Bioheng has made impressive progress in both universal CAR-T and enhanced CAR-T [therapies] for solid tumor, and achieved outstanding clinical results," June said. "I look forward to a faster clinical application and sooner benefit to cancer patients."


US News

Mandates, not recommendations, work best to get folks vaccinated: Study

PIK Professor Dolores Albarracín authored a study that found mandates are more likely to lead to vaccine uptake than suggestions. “The requirement condition works better across the board, for different racial and ethnic groups and even among people who dislike feeling and being controlled by others,” she said.


The New York Times

Waiting on U.S. mandate, some nursing homes are slow to vaccinate staff

PIK Professor Ezekiel Emanuel said lower COVID-19 vaccination rates lead to more infections. “We should be clear that mandates have been working and have been working in every industry that has tried them,” he said.


ABC News

Why breakthrough COVID deaths can be misunderstood

Edward Stadtmauer of the Perelman School of Medicine advised cancer patients to get vaccinated against COVID-19. “If you have abnormal plasma cells to begin with or are getting therapy that might suppress or damage plasma cells, you can see why that this group of patients may have the most difficulty responding to a COVID infection and responding to vaccines,” he said. “If there is any group of patients who should be vaccinated and get a booster, it is this group of patients.”