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Tumor-on-a-chip offers insight into cancer-fighting cells in immunotherapy
Hand holding a microdevice

Penn engineers and collaborators have developed a transparent, micro-engineered device that houses a living, vascularized model of human lung cancer—a “tumor on a chip”—and show that the diabetes drug vildagliptin helps more CAR T cells break through the tumor’s defenses and attack it effectively.

(Image: Courtesy of Dan Huh)

Tumor-on-a-chip offers insight into cancer-fighting cells in immunotherapy

Penn engineers and collaborators have built a living tumor on a chip to expose how cancers block immune attacks, and how one existing drug could make immunotherapy like CAR T more effective against solid tumors.

3 min. read

Through Penn First Plus, students unlock potential and purpose
Marc Lo (left) and Enmanuel Martínez (center) speaking with Mayokun Omitogun (right)

Marc Lo (left) and Enmanuel Martínez (center) speaking with Mayokun Omitogun (right)

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Through Penn First Plus, students unlock potential and purpose

Providing first-generation and limited-income students with a comprehensive array of support, Penn First Plus equips undergraduates for success during and after their time at Penn.

5 min. read

Bringing the US Navy’s 250-year history to life
J.J. Ahern stands in a storage area in the University Archives.

Penn archivist J.J. Ahern.

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Bringing the US Navy’s 250-year history to life

Penn archivist J.J. Ahern has been putting his professional experience and personal passion for the past to work as a volunteer for the Navy’s 250th anniversary curating an exhibition about the human side of the service’s history.

3 min. read

Using artificial intelligence to improve public health campaigns across Philadelphia

Using artificial intelligence to improve public health campaigns across Philadelphia

Annenberg School for Communication professor Andy Tan and research associate and Lecturer Matthew Brook O'Donnell are interested in how artificial intelligence could make it easier for community-based organizations to improve public health in Philadelphia.

2025 Bioethics Founders’ Award

2025 Bioethics Founders’ Award

George A. Weiss University Professor of Law and Sociology & Raymond Pace and Sadie Tanner Mossell Alexander Professor of Civil Rights Dorothy E. Roberts has been named a recipient of the 2025 Bioethics Founders’ Award, which recognizes individuals who have made substantial, sustained contributions to bioethics in ways that have advanced thinking and practice in medicine, the life sciences, and public policy.

$27.2M national effort launches to unify Alzheimer’s research data

$27.2M national effort launches to unify Alzheimer’s research data

Yong Chen, Leonard Davis Institute senior fellow and professor of biostatistics, epidemiology, and informatics at the Perelman School of Medicine, has been selected by the National Institute on Aging initiative to establish a collaborative network and data ecosystem to accelerate discovery and improve prevention, detection, and treatment strategies for Alzheimer’s disease and related dementias.

Harnessing technology in research to improve well-being
Tony Shaw, Dennis Culhane, Isabel Algrant, Ken Miles, and Shana Kleiner at table.

As part of the year-long Politics of Well-Being series from the School of Social Policy & Practice and the Andrea Mitchell Center for the Study of Democracy, Tony Shaw moderated a conversation with Dennis Culhane, Isabel Algrant, Ken Miles, and Shana Kleiner.

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Harnessing technology in research to improve well-being

As part of the Politics of Well-Being speaker series, researchers in the School of Social Policy & Practice talked about their work helping governments address social issues and creating a joy-centered framework for AI development.

3 min. read

Understanding AI actress Tilly Norwood’s arrival

Understanding AI actress Tilly Norwood’s arrival

Tilly Norwood, the “AI actress” recently making headlines, has sparked debate in the media industry about the future of AI in filmmaking. Annenberg experts weigh in on what Norwood represents for creativity, ethics, and the evolving relationship between technology and performance.

Penn Engineering receives $11M from the A. James & Alice B. Clark Foundation to expand Clark Scholars Program
(bottom row, left to right) Tina Lee, Amehja Williams, and Hubery Pai; (second row) Amaris Chen and Ross Richard; (third row) Darren Lin, Minghui Zhang, Emily Jiang, and Frankie Lin; (fourth row) Shawn Edbert, Henry Westfall, and Noah Hidalgo; (fifth row) Matas Bujanauskas and Elias Chavez.

Penn Clark Scholars and peer mentors: (bottom row, left to right) Tina Lee, Amehja Williams, and Hubery Pai; (second row) Amaris Chen and Ross Richard; (third row) Darren Lin, Minghui Zhang, Emily Jiang, and Frankie Lin; (fourth row) Shawn Edbert, Henry Westfall, and Noah Hidalgo; (fifth row) Matas Bujanauskas and Elias Chavez.

(Image: Courtesy of Penn Engineering)

Penn Engineering receives $11M from the A. James & Alice B. Clark Foundation to expand Clark Scholars Program

The funds will strengthen scholarships, create an annual Philanthropy Challenge, establish an entrepreneurship concentration, and support summer internships for future engineering leaders.

Holly Wojcik

2 min. read