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  • Versatile ‘chemoproteomic probes’ for activity-based protein profiling

    A new study uses organohydrazine probes to map chemical reactivty across the proteome, allowing for a diverse classes of proteins and biological pathways to be studied.
    an abstract globe with DNA helixes, a brain outline, and chemical symbols
    New research from the lab of Megan Matthews describes a versatile method for mapping hundreds of diverse enzyme sites and protein functions. These new findings enable diverse classes of proteins and biological pathways to be profiled and specific, targeted therapeutics to be developed for a broad range of diseases. (Image: Matthews Lab)

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  • Exposure to air pollution worsens Alzheimer’s disease
    Emissions from a power plant.

    Image: Pencho Chukov via Getty Images

    Exposure to air pollution worsens Alzheimer’s disease

    New research from Penn Medicine finds living in areas with high concentration of air pollution is associated with increased buildup of amyloid and tau proteins in the brains of Alzheimer’s patients, accelerating cognitive decline.

    Sep 9, 2025

    Penn physicist Charles Kane to receive the 2026 Lorentz Medal
    Charles Kane

    Charles Kane, Christopher H. Browne Distinguished Professor of Physics at Penn’s School of Arts & Sciences.

    (Image: Brooke Sietinsons)

    Penn physicist Charles Kane to receive the 2026 Lorentz Medal

    Awarded every four years by the Royal Netherlands Academy of Arts and Sciences, the medal honors Kane’s pioneering research on topological insulators.

    Sep 4, 2025