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Making ‘true’ equine IVF a reproducible success
Three foals and two mares in a pasture

Making ‘true’ equine IVF a reproducible success

A new method developed by Katrin Hinrichs and colleagues in the School of Veterinary Medicine resulted in the birth of three healthy foals, opening the door to new insights in the basic biology of horse reproduction.

Katherine Unger Baillie

A decade of advancing working dogs for the greater good
new litter of penn working dogs

(Homepage image) Puppies at the Penn Vet Working Dog Center, like these black Labs of the “U litter,” begin their formal training at the tender age of 8 weeks, an unusual feature of the program. Playtime is an important part of that preparation, building confidence and improving physical and social skills.

A decade of advancing working dogs for the greater good

Inspired by her experience caring for working dogs following 9/11 at Ground Zero, Penn Vet Working Dog Center Director Cynthia Otto’s initial vision has grown into a thriving organization with a mission to use science to improve the breeding, training, care, and effectiveness of working dogs.

Katherine Unger Baillie

T cells that ‘nibble’ tumors unwittingly help cancer evade the immune response
Fluorescent microscopic image of three T cells surrounding a cancer cell

Tcells surround a cancer cell to finish it off, but such interactions do not always end with the T cells victorious. Researchers from Penn detail how cancer cells can prompt T cells to ingest bits of cancer cell membrane, a process known as trogocytosis. The cancer may evade immune detection as a result. (Image: Alex Ritter, Jennifer Lippincott Schwartz and Gillian Griffiths, National Institutes of Health)

T cells that ‘nibble’ tumors unwittingly help cancer evade the immune response

Blocking this process, known as trogocytosis, improved the ability of a CAR T cell therapy to treat cancer in mice, according to research led by School of Veterinary Medicine scientists.

Katherine Unger Baillie

Cooler temps and northern climes associated with increased diabetes diagnoses in dogs
A reclining dalmatian dog is examined by a provider with a stethoscope

A team from Penn Vet has identified an association between colder weather and climates and diabetes diagnoses in dogs. A parallel link is seen in diagnoses of Type 1 diabetes in people. 

Cooler temps and northern climes associated with increased diabetes diagnoses in dogs

Mirroring a finding in humans, diabetes diagnoses in dogs were more common in colder areas of the U.S. and during winter, according to a new study led by School of Veterinary Medicine researchers.

Katherine Unger Baillie

How to improve accessibility and digital inclusion
Hands typing on a keyboard.
  • Q&A

    • How to improve accessibility and digital inclusion

    Tonya Bennett discusses a recent accessibility awareness panel discussion where higher education leaders focused on physical and digital access and inclusion for the more than one billion people worldwide with disabilities and impairments.

    Dee Patel

    The Gambia Goat Dairy builds sustainability through community
    A woman takes the heartbeat of a goat while two men secure the goat.

    Abby Seeley (center) of Penn Vet does a health check up on a goat with the assistance of Sulay Camara (left) and Sainey Badjie (right). (Image: Courtesy of Brianna Parsons)

    The Gambia Goat Dairy builds sustainability through community

    Since its founding by Penn Vet students in 2016, the Gambia Goat Dairy has worked in partnership with Gambians to serve its community. The research and teaching farm also gives current students the opportunity to use their veterinary skills for social good.

    Luis Melecio-Zambrano

    Progress toward a stem cell–based therapy for blindness
    Fluorescent microscopy against a black background shows a layer of green flecks over a mix of blue and red labeled cells

    Progress toward a stem cell–based therapy for blindness

    A multi-institutional effort led by researchers at the School of Veterinary Medicine is taking steps to develop an effective technique to regenerate photoreceptors cells and restore sight in people with vision disorders.

    Katherine Unger Baillie

    A newly identified stem cell regulator enables lifelong sperm production
    Illustration of different cell types that eventually give rise to sperm shows that blocking an early stage of cell development can prevent the formation of sperm

    When the enzyme DOT1L is not functional, spermatogonial stem cells become exhausted, leading to a failure of sperm cell development. This crucial role for DOT1L places it in rarefied company as one of just a handful of known stem cell self-renewal factors, a Penn Vet team found. (Image: Courtesy of Jeremy Wang)

    A newly identified stem cell regulator enables lifelong sperm production

    Research led by Jeremy Wang of the School of Veterinary Medicine has discovered that the enzyme DOT1L, a stem cell renewal factor, is essential for mice to produce sperm throughout their adult lives.

    Katherine Unger Baillie

    A $365 million development will expand the life sciences hub at Pennovation Works
    Rendering depicting aerial view of new life sciences building on Pennovation Works campus

    A $365 million development will expand the life sciences hub at Pennovation Works

    Penn Senior Executive Vice President Craig Carnaroli speaks with Penn Today about the evolution of the research and manufacturing project, led by Longfellow Real Estate Developers, and its value for Penn and the region.

    Katherine Unger Baillie

    A Penn Vet tale: Olive, the tiny little fighter
    A small wide-eyed Shi Tzu holds large boxing gloves in its mouth.

    Illustration by Jon Krause.

    A Penn Vet tale: Olive, the tiny little fighter

    When Olive, the four-month-old Shih Tzu mix, became critically ill with respiratory distress, clinicians at Penn Vet’s Ryan Hospital spent a week collaborating on intensive treatment.

    Sacha Adorno