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Researchers breathe new life into lung repair
Artist's interpretation of human lungs and a virus.

Respiratory diseases like influenza and COVID-19 drive inflammatory responses that can cause long-term damage to the lungs and can be difficult to treat. Now, by using techniques that deliver mRNA via lipid nanoparticles, researchers led by Andrew Vaughan of the School of Veterinary Medicine were able to greatly enhance modes of repair for damaged blood vessels in the lung, leading to improved oxygen saturation.

(Image: iStock/Mohammed Haneefa Nizamudeen)

Researchers breathe new life into lung repair

A collaborative effort from teams across Penn culminates in new techniques to repair lung tissue after damage from flu and COVID-19.
Targeted anti-smoking messages for LGBTQ+ young women
A teen’s hand holding a cigarette.

Image: iStock/serikbaib

Targeted anti-smoking messages for LGBTQ+ young women

In an effort to understand how to reduce smoking among LGBQT+ young women, Professor Andy Tan and colleagues tested tailored anti-smoking campaigns.

From Annenberg School for Communication

Breaching the blood-brain barrier
Researchers Mike Mitchell and Emily Han examining a microfluidic device used to make LNPs by mixing lipids and mRNA.

Michael Mitchell (left) and Emily Han (right) examine a microfluidic device used to make LNPs by mixing lipids and mRNA. 

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Breaching the blood-brain barrier

A team of researchers in the School of Engineering and Applied Sciences has devised a method to deliver mRNA into the brain using lipid nanoparticles, potentially advancing treatments for Alzheimer’s disease and seizures.
Two-and-a-half decades of research in Malawi
Malawi Longitudinal Study of Families and Health Collaborators on the Malawi Longitudinal Study of Families and Health visited the University of Pennsylvania in October for a project meeting. Pictured are Lauren Schmitz (University of Wisconsin-Madison), Namrata Ray (Penn), Hans-Peter Kohler (Penn), Kondwani Katundu (Kamuzu University of Health Sciences in Malawi), Kazione Kulisewa (Kamuzu University), Iliana V. Kohler (Penn), and Victor Mwapasa (Kamuzu University).

(Image: Eric Sucar)

Two-and-a-half decades of research in Malawi

As the country’s life expectancy has risen, the Malawi Longitudinal Study of Families and Health has shifted its current and future research to aging.
Climate change and atmospheric dynamics unveil future weather extremes
Canal middle agricultural dry by drought and heatwave on summer. water crisis and water stress on summer during long term drought on summer.

A collaborative team of researchers led by Michael Mann of the School of Arts & Sciences have found the interplay of natural systems and human-induced climate change are setting the stage for more frequent and severe weather events.

(Image/iStock / Piyaset)

Climate change and atmospheric dynamics unveil future weather extremes

A collaborative team of researchers led by Michael Mann of the School of Arts & Sciences have found the interplay of natural systems and human-induced climate change are setting the stage for more frequent and severe weather events.