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Cancer cells selectively load ‘drones’ to keep T cells from infiltrating tumors
four panels show a cancerous tumor with some portions labeled in red, green, and blue, and a close up image of part of it

The researchers found that levels of phosphorylated HRS varied across tumors, negatively corresponding with the level of T cell infiltration in those areas. (Image: Guo lab/Nature Communications)

Cancer cells selectively load ‘drones’ to keep T cells from infiltrating tumors

Biologist Wei Guo and colleagues elucidate the process of sorting and loading cargo for these biological drones with implications for a more targeted and effective use of checkpoint inhibitor drugs in cancer treatment.

Katherine Unger Baillie

Progress toward a stem cell–based therapy for blindness
Fluorescent microscopy against a black background shows a layer of green flecks over a mix of blue and red labeled cells

Progress toward a stem cell–based therapy for blindness

A multi-institutional effort led by researchers at the School of Veterinary Medicine is taking steps to develop an effective technique to regenerate photoreceptors cells and restore sight in people with vision disorders.

Katherine Unger Baillie

TV news top driver of political echo chambers in U.S.
An illustration of an old television with a person in sunglasses on it. On top sits a laptop computer with an arm reaching out past the screen, holding a rolled up newspaper. Another newspaper lays flat on top of the screen.

TV news top driver of political echo chambers in U.S.

Duncan Watts and colleagues found that 17% of Americans consume television news from partisan left- or right-leaning sources compared to just 4% online. For TV news viewers, this audience segregation tends to last month over month.

Michele W. Berger

Intervening to stop bone loss
Penn Dental Medicine professor Shuying Yang

Shuying (Sheri) Yang

nocred

Intervening to stop bone loss

A study led by Shuying (Sheri) Yang of the School of Dental Medicine identified a new role for a protein that keeps osteoclasts—the cells that break down bone—in check, and may guide the development of new therapies to counter bone loss.

Katherine Unger Baillie

Testing, treatments, and more: A glossary for year three of the pandemic
Illustration of people talking about the coronavirus pandemic

The lexicon of the coronavirus pandemic continues to expand as new knowledge about COVID-19 emerges. 

Testing, treatments, and more: A glossary for year three of the pandemic

Penn Today adds a new installment to this series aimed at making sense of the language around COVID-19.

Marilyn Perkins

A cleaner, greener airport of the future
Six students stand around a poster with wind turbines and airplanes on it

A cleaner, greener airport of the future

Six students from across the University presented their vision of an airport equipped with carbon-capturing technology and an electrified vehicle fleet at a NASA competition, garnering the “Most Intriguing Concept” award.

Katherine Unger Baillie

The Supreme Court restricts the EPA’s power to curb climate change
Smoke from a power plant clouds out the sun's light

With the decision in West Virginia v. the U.S. Environmental Protection Agency, the Supreme Court ruled to limit the EPA’s capacity to regulate power plant emissions under the Clean Air Act. The move hamstrings efforts by the federal government to regulate a major contributor to climate change.

  • Q&A

    • The Supreme Court restricts the EPA’s power to curb climate change

    Shelley Welton, a new faculty member with Penn Carey Law and the Kleinman Center for Energy Policy, calls the decision “devastating,” even if expected. She explains the ruling and its implications for action on climate change.

    Katherine Unger Baillie

    Penn and the Science History Institute to serve as new hosts of History of Science Society
    Conference meeting with dozens of people seated and looking at a presentation in a church-like setting

    With its relocation to Philadelphia, the History of Science Society will have a home base at Penn and the Science History Institute from which to receive support, host events, and interact with the city’s robust scholarly community. (Image: Courtesy of HSS)

    Penn and the Science History Institute to serve as new hosts of History of Science Society

    The arrangement highlights Philadelphia as a hub for history of science scholarship and will provide mentoring opportunities for Penn students.

    Katherine Unger Baillie

    Parental nicotine use and addiction risk for children
    A put-out cigarette standing on its end, next to half of another crumpled cigarette. In the background are two whole cigarettes.
  • Q&A

    • Parental nicotine use and addiction risk for children

    In research done using rats, Penn Nursing’s Heath Schmidt and colleagues found that males that engaged in voluntary nicotine use had offspring more likely to do so, too. Some offspring also developed impaired memory and anxiety-like behavior.

    Michele W. Berger