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A serendipitous find leads to lifesaving discoveries
Fluorescent imaging of glioblastoma under a microscope.

Image: Kyosuke Shishikura

A serendipitous find leads to lifesaving discoveries

A Penn-led team has revealed a how hydralazine, one of the world’s oldest blood pressure drugs and a mainstay treatment for preeclampsia, works at the molecular level. In doing so, they made a surprising discovery—it can also halt the growth of aggressive brain tumors.

3 min. read

Nanoparticle blueprints reveal path to smarter medicines
Hannah Yamagata, Research Assistant Professor Kushol Gupta and postdoctoral fellow Marshall Padilla, holding 3D-printed models of nanoparticles in a lab.

(From left) Doctoral student Hannah Yamagata, research assistant professor Kushol Gupta, and postdoctoral fellow Marshall Padilla holding 3D-printed models of nanoparticles.

(Image: Bella Ciervo)

Nanoparticle blueprints reveal path to smarter medicines

New research involving Penn Engineering shows detailed variation in lipid nanoparticle size, shape, and internal structure, and finds that such factors correlate with how well they deliver therapeutic cargo to a particular destination.

Ian Scheffler

2 min. read

‘Meet the Authors’: A roundup of Wharton faculty in print

‘Meet the Authors’: A roundup of Wharton faculty in print

The “Ripple Effect” podcast from the Wharton School highlights books from four faculty members on ”having it all” in the workplace, hybrid and remote work, “hidden markets,” and creativity and AI.

From Knowledge at Wharton

2 min. read

National Academy of Medicine issues code of conduct to guide health care’s AI revolution

National Academy of Medicine issues code of conduct to guide health care’s AI revolution

LDI senior fellow and Penn professor with appointments in the Perelman School of Medicine, the School of Engineering and Applied Science, and the Annenberg School for Communication Kevin B. Johnson is one of the authors of the new National Academy of Medicine AI code of conduct guide for Health Care.

Beth Simmons named president of the American Political Science Association

Beth Simmons named president of the American Political Science Association

Beth Simmons, University of Pennsylvania Carey Law School Andrea Mitchell University Professor in Law, Political Science and Business Ethics, has been named president-elect of the American Political Science Association for 2026-27.

How a coral stiffens its skeleton on demand
Chenhao Hu holds up a 3D-printed model of a sclerite.

Penn Engineering doctoral student Chenhao Hu holding a 3D-printed model of a sclerite, the tiny mineral particles that make up the coral’s skeleton and whose unique shape allows the organism to tune its own stiffness.

(Image: Bella Ciervo)

How a coral stiffens its skeleton on demand

Researchers at Penn Engineering have discovered how a coral’s skeleton compacts itself to ward off danger, a novel discovery of “granular jamming” in a living organism.

Ian Scheffler

2 min. read

Why even impartial judges can seem biased

Why even impartial judges can seem biased

Penn Carey Law professor Leo Katz explains how the selection effect and judicial strategy can make merit-based rulings look indistinguishable from politically motivated or random decisions.

From Penn Carey Law

2 min. read

What big data says about rising home insurance rates

What big data says about rising home insurance rates

Wharton real estate professor Benjamin Keys shares how real estate data is shedding new light on everything from smart investment decisions to mounting insurance costs in risky climates.