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Innate immune training aggravates inflammatory bone loss
Osteoclasts resorbing bone

Image: Love Employee via Getty Images

Innate immune training aggravates inflammatory bone loss

Researchers from the School of Dental Medicine and international collaborators from Germany have investigated the effects of training the innate immune system in experimental models of chronic inflammatory disease, periodontitis and arthritis.
Q&A on the German election results
The dome of a building is visible on the left. To the right, a striped black, red and yellow flag is flying on a pole. An inscription on the building reads: “Dem Deutschen Volke,” or “To the German People.”

The German flag flies in front of the Reichstag building the day after the German Bundestag elections were held.

(Image: Christophe Gateau/picture-alliance/dpa/AP Images)

  • Q&A

    • Q&A on the German election results

    Kristen Ghodsee of the Department of Russian and East European Studies discusses the outcome of the German parliamentary elections and the implications for Europe’s future.
    Building bridges: A feat of engineering and artistry
    The Glass Bridge

    Architect Masoud Akbarzadeh and research assistant Boyu Xiao of the Weitzman School of Design, along with collaborators including Yao Lu of Jefferson University, defied conventional engineering by constructing a 30-foot-long bridge entirely from 16 millimeter hollow glass units. Their effort is now showcased at the Corning Museum of Glass.

    (Image: Courtesy of the Corning Museum of Glass)

    Building bridges: A feat of engineering and artistry

    At the Corning Museum of Glass, professor of architecture Masoud Akbarzadeh and his team have turned fragility into strength with a 30-foot-long span of shimmering glass, blending ancient wisdom with cutting-edge design to redefine the future of structural engineering and architecture.

    9 min. read

    Corine Labridy leads an exploration of French Caribbean culture and literature
    A woman with glasses in a dark sweater sits behind a desk, looking to the left.

    Corine Labridy, an assistant professor of French and Francophone studies, uses the literature of the French Caribbean to help students learn larger lessons about identity and culture.

    (Image: Corine Labridy)

    Corine Labridy leads an exploration of French Caribbean culture and literature

    The French and Francophone Studies faculty member took an unconventional route to academia. She places the voices of the islands at the heart of her work.
    Getting to the root of root canals
    Person receiving treatment in a dental clinic.

    Image: Courtesy of Penn Dental Medicine/Peter Olson Photography

    Getting to the root of root canals

    Penn researchers use iron oxide nanozymes to treat infections during root canals with fewer adverse effects than clinical gold standard while also promoting tissue healing.
    Sophia Z. Lee: ‘The Reconciliation Roots of Fourth Amendment Privacy’
    Person with arms crossed stands outside Law School

    Sophia Z. Lee

    (Image: Penn Carey Law)

    Sophia Z. Lee: ‘The Reconciliation Roots of Fourth Amendment Privacy’

    The dean of the University of Pennsylvania Carey Law School explores “privacies of life” and Fourth Amendment rights in the University of Chicago Law Review.

    From Penn Carey Law

    Four from Penn named 2025 Sloan Research Fellows
    Four portraits arranged in a 2x2 grid. Clockwise from top left: Jason Altschuler, Cesar de la Fuente, Liang Wu, and Anderson Ye Zhang

    Jason Altschuler (top left) and Anderson Ye Zhang (bottom left) of the Wharton School, Liang Wu (bottom right) of the School of Arts & Sciences, and César de la Fuente (top right) of the Perelman School of Medicine have been named 2025 Sloan Research Fellows. They are among 126 early-career scientists in North America chosen this year to receive the two-year, $75,000 fellowship in recognition of their accomplishments, creativity, and potential to become leaders in their fields.

    nocred

    Four from Penn named 2025 Sloan Research Fellows

    Jason Altschuler, César de la Fuente, Liang Wu, and Anderson Ye Zhang have been honored as early-career researchers and scholars for their accomplishments, creativity, and potential to become leaders in their fields.
    Pursuing vaccines to stop celiac disease
    A researcher holding a vaccine vial in a lab next to a microscope.

    Image: iStock/nuttapong punna

    Pursuing vaccines to stop celiac disease

    Scientists at Penn’s Institute for RNA Innovation are using messenger RNA to stop the immune response that triggers celiac disease symptoms.

    Alex Gardner

    Looking to the past to understand the impacts of human land use in South Asia
    R. Ramesh adjusts measuring tape at archaeological site.

    R. Ramesh, assisting superintending archaeologist at the Archaeological Survey of India, adjusted a measuring tape at an archaeological site in India before he and Penn's Kathleen Morrison took samples for paleoenvironmental analysis from a Neolithic (3000-1200 BCE) deposit. 

    (Image: Courtesy of Kathleen Morrison)

    Looking to the past to understand the impacts of human land use in South Asia

    An international group of scholars, including archaeologists from the School of Arts & Sciences, synthesized archaeological evidence in South Asia from 12,000 and 6,000 years ago.

    5 min. read

    Is Moore’s Law really dead?
    A semiconductor wafer.

    According to Moore’s Law, the number of transistors on an integrated circuit will double every two years.

    (Image: iStock/SweetBunFactory)

    Is Moore’s Law really dead?

    Penn Engineering’s Ben Lee and André DeHon discuss Moore’s Law, the observation that the number of transistors on an integrated circuit will double every two years with minimal rise in cost, and reflect on the consequences and opportunities of its possible end.

    Devorah Fischler