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$2.6M NIH grant backs search for genetic cure in deadly heart disease

$2.6M NIH grant backs search for genetic cure in deadly heart disease

Sherry Gao, Presidential Penn Compact Associate Professor in chemical and biomolecular engineering and in bioengineering at Penn Engineering is the co-recipient of a $2.6 million grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to develop new gene editing tools that could address one of the underlying mutations that causes hypertrophic cardiomyopathy, a genetic disease that thickens the heart’s walls, making it harder for the organ to pump blood.

Rethinking ‘one-teacher, one-classroom’
Two teachers having a discussion in a classroom.

Image: SolStock via Getty Images

Rethinking ‘one-teacher, one-classroom’

A new study by Penn GSE’s Richard Ingersoll evaluates a team-based model of organizing teaching staff in elementary and secondary schools that integrates teams of teaching staff in contrast to this traditional one-teacher, one-classroom approach.

From Penn GSE

2 min. read

Can data from the Large Hadron Collider snap string theory?
Close-up of ATLAS detector at CERN.

ATLAS’s wheel-like end-cap reveals the maze of sensors primed to catch proton smash-ups at the LHC. Researchers comb through billions of events in search of fleeting “ghost” tracks that might expose cracks in string theory.

(Image: Courtesy of CERN)

Can data from the Large Hadron Collider snap string theory?

Theoretical physicist Jonathan Heckman of the School of Arts & Sciences has put a spin on ideas related to testing string theory: Rather than looking to verify it, he and his collaborators sought a novel way to falsify it. Heckman and Ph.D. candidate Rebecca Hicks explain string theory, researchers’ quest to unify physics, and what their new paper puts forward.

10 min. read

Transforming CAR T treatment: ‘Leukemia-on-a-chip’
The actual chip of human leukemia bone marrow where chambers and channels were filled with food dyes.

The actual chip of human leukemia bone marrow where chambers and channels were filled with food dyes.

(Image: NYU Tandon Applied Micro-Bioengineering Laboratory/Courtesy of Weiqiang Chen)

Transforming CAR T treatment: ‘Leukemia-on-a-chip’

In a collaborative effort with NYU, Penn researchers have helped pioneer a novel 3D platform that mimics the human bone marrow and immune environment, enabling more predictive testing of cancer immunotherapy success in patients, including CAR T cell therapies.

3 min. read

Irina Marinov: How to prepare for the impacts of a changing climate
Irina Marinov

Irina Marionov is a climate scientist and a associate professor in the Department of Earth and Environmental Sciences School of Arts & Sciences at the University of Pennsylvania.

nocred

Irina Marinov: How to prepare for the impacts of a changing climate

Irina Marinov, associate professor at the Department of Earth and Environmental Science, leads a research community focused on understanding global climate impacts, risks, and vulnerabilities to enable local action.

From the Environmental Innovations Initiative

2 min. read

Teaching robots to build without blueprints
A simulation of the mathematics of a bee colony.

Researchers at Penn Engineering have developed mathematical rules to simulate robots to behave like bees, building complex shapes without instructions, pointing to a new manufacturing frontier.

(Image: Courtesy of Jordan Raney and Mark Yim)

Teaching robots to build without blueprints

Researchers at Penn Engineering have developed mathematical rules to simulate robots who behave like bees, building complex shapes without instructions, pointing to a new manufacturing frontier inspired by nature.

Ian Scheffler

2 min. read

Nurse practitioner award for Selena Ann Gilles

Nurse practitioner award for Selena Ann Gilles

Gilles, a practice professor in the Department of Biobehavioral Health Sciences and associate dean for School and Community Engagement at Penn Nursing, has been named a recipient of the& 2025 AANP State Award for Outstanding Contributions by the American Association of Nurse Practitioners.