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  • Unlocking the female bias in lupus

    New research on the X chromosome from the School of Veterinary Medicine points to an abnormality in the immune system’s T cells as a possible contributing factor in lupus and other autoimmune diseases.
    Two panels, each with an inset images, show blue cells with pink genetic material highlighted. The pink areas are defined in the left panel and more diffuse in the right panel.
    Patterns of the RNA molecule Xist (labeled pink), which is responsible for X chromosome inactivation, differed between healthy patients' T cells and T cells from lupus patients. In female lupus patients, Xist appeared in a diffuse cloud, rather than in a targeted pattern, across the nuclei of activated T cells. This mislocalization, Penn researchers say, may lead to abnormal gene expression that contributes to the autoimmune disease. (Image: Anguera lab)

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  • From a desert to an oasis: Penn engages in ambitious greening effort in the Sahel
    People gather around a large map placed on the floor.

    In Senegal, the ambitious Dakar Greenbelt project seeks to create an extensive network of ecological infrastructure in and around the city to sustainably address environmental concerns and enhance urban life. With support from David Gouverneur and Ellen Neises, Ph.D. candidate Rob Levinthal in the Weitzman School of Design led two courses that included a field trip to Dakar, that culminated in students presenting their visions for parts of the Greenbelt.

    (Image: Courtesy of Chaowu Li)

    From a desert to an oasis: Penn engages in ambitious greening effort in the Sahel

    Students from the Weitzman School of Design journeyed to Senegal to help with a massive ecological and infrastructural greening effort as part of their coursework. The Dakar Greenbelt aims to combat desertification and promote sustainable urban growth.

    Jan 31, 2025

    An illuminating celebration to a brighter, greener future
    The exterior of the Vagelos building lit up with dramatic lighting.

    The new Vagelos Laboratory for Energy Science and Technology boasts adaptable laboratory spaces to support the dynamic needs of pioneering research.

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    An illuminating celebration to a brighter, greener future

    Members of the Penn community celebrated an energy research milestone: the unveiling of the new Vagelos Laboratory for Energy Science and Technology.

    Dec 12, 2024