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Decoding ancient immunity networks
Hand holding a blood vial that reads "complement (C3 + C4)"

A collaborative team from the School of Engineering and Applied Science and the Perelman School of Medicine have unraveled the mathematics of a 500-million-year-old protein network that acts like the body’s bouncer, “deciding” which foreign materials get degraded by immune cells and which are allowed entry.

(Image / iStock Md Saiful Islam Khan)

Decoding ancient immunity networks

A collaborative team from Penn Medicine and Penn Engineering have  unraveled the mathematics of a 500-million-year-old protein network that “decides” which foreign materials are friend or foe.

Nathi Magubane , Ian Scheffler , Holly Wojcik , Matt Toal

5 min. read

Who, What, Why: Xiao Schutte Ke on Tibetan pastoralists and citizen science
Xiao Schutte Ke.

Image: Courtesy of Xiao Schutte Ke

Who, What, Why: Xiao Schutte Ke on Tibetan pastoralists and citizen science

Schutte Ke, a sixth-year linguistic anthropology doctoral candidate in the School of Arts & Sciences, explains the importance of Indigenous citizen scientists in understanding a crucial ecosystem of nomadic livestock herders on the mountainous region of the Tibetan Plateau.

3 min. read

What can ants and naked-mole rats teach about societal roles?
Leafcutter ants moving around a bright green leaf.

In eusocial superorganisms like leafcutter ant colonies, labor is divvied up according to body shape and size, but PIK Professor Shelley Berger and her team discovered that molecular signals can override that blueprint. Their findings reveal how simple neuropeptides can reprogram ant behavior, reshuffling roles in nature’s most disciplined workforce.

(Image: Courtesy of Tierney Scarpa)

What can ants and naked-mole rats teach about societal roles?

PIK Professor Shelley Berger and colleagues explored the genetic basis of labor distribution in communal-dwelling species and discovered that pathways dating back hundreds of millions of years are conserved across animal kingdoms. Their findings offer fundamental insights into complex social behaviors.

5 min. read

The perils and promise of GLP-1 medications
A doctor taking the blood pressure of a patient

Image: rudi_suardi via Getty Images

The perils and promise of GLP-1 medications

How Penn Nursing researchers are ahead of the curve.

From Penn Nursing News

5 min. read

How cable news has diverged from broadcast news
Person sitting on couch watching news.

Image: simonkr via Getty Images

How cable news has diverged from broadcast news

A team of researchers from the Computational Social Science Lab at the University of Pennsylvania find that cable news has increasingly diverged from broadcast news in the topics covered and language used.

3 min. read

$50 million gift to launch the Lurie Autism Institute
Jeffrey Lurie speaking at the podium.

Jeffrey Lurie, CEO and Chairman of the Philadelphia Eagles, speaks at an event announcing the Lurie Autism Institute, a joint initiative between CHOP and Penn Medicine.

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$50 million gift to launch the Lurie Autism Institute

The transformational gift to Penn Medicine and Children’s Hospital of Philadelphia will establish a joint initiative for autism research and treatment.

4 min. read

Could gene therapy restore lost hearing?
Soundwaves superimposed over an ear.

Image: Courtesy of Penn Medicine Magazine

Could gene therapy restore lost hearing?

Experts at Penn Medicine are working to understand the genetic architecture of hearing loss in adults at the Penn Center for Adult-Onset Hearing Loss.

From Penn Medicine Magazine

2 min. read

The FBI’s secret impact on American broadcasting

The FBI’s secret impact on American broadcasting

A new Annenberg School for Communication study of declassified FBI files documents how the Bureau wielded the fear of communist infiltration to infiltrate the broadcasting industry itself.

Improving care for disadvantaged patients

Improving care for disadvantaged patients

New research from Penn Nursing provides insight on the critical factors that help or hinder hospital nurses in delivering quality care to socially disadvantaged patients.

From Penn Nursing News

1 min. read

AI x Science Postdoctoral Fellows collaborate across disciplines
Sibe-by-side portraits of Brynn Sherman, on left, and Kieran Murphy, right.

Penn’s AI x Science Postdoctoral Fellows Program is breaking down traditional scientific boundaries by integrating artificial intelligence across diverse research fields. Less than a year in, the program is already paying dividends in the form of new collaborations and research publications for inaugural fellows like Brynn Sherman (left) of the School of Arts & Sciences and Kieran Murphy (right) of the School of Engineering and Applied Science.

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AI x Science Postdoctoral Fellows collaborate across disciplines

The new fellowship program, offered through the School of Arts & Sciences and the School of Engineering and Applied Science, offers mentorship and peer engagement opportunities.

5 min. read