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A built-in ‘off switch’ to stop persistent pain

Collaborative research on the neural basis of chronic pain led by neuroscientist J. Nicholas Betley finds that a critical hub in the brainstem, has a built-in “off switch” to stop persistent pain signals from reaching the rest of the brain. Their findings could help clinicians better understand chronic pain. (Pictured) Flurorescence imaging reveals hunger neurons in the arcuate nucleus of the hypothalamus labeled in maroon with nuclei shown in blue.

(Image: J. Nicholas Betley)

A built-in ‘off switch’ to stop persistent pain

J. Nicholas Betley has led collaborative research seeking the neural basis of long-term sustained pain and finds that a critical hub in the brainstem holds a mechanism for stopping pain signals from reaching the rest of the brain. Their findings could help clinicians better understand chronic pain and lead to new, more efficacious treatments.

4 min. read

A new Penn Vet study is finding where the wild things are
A deer by a river in nature.

Image: Courtesy of Penn Vet

A new Penn Vet study is finding where the wild things are

The Accessing Urban Nature Initiative is gathering data on how urban wildlife is using the Philadelphia region’s ecosystem with motion-triggered cameras around Philadelphia parks, cemeteries, forest preserves, and private land.

From Penn Vet

2 min. read

Students benefit most when teachers share both their background and language skills

Students benefit most when teachers share both their background and language skills

A new study coauthored by Graduate School of Education’s Michael A. Gottfried is the first to show that teachers’ ability to teach in students’ home language, combined with a shared racial or ethnic background, drives greater academic gains.

On collaborating with Jane Goodall
Jane Goodall is seen from a front-facing view.

Jane Goodall, the internationally renowned primate researcher, died at age 91.

(Image: Yui Mok/PA Wire/PA Images via AP Images)

On collaborating with Jane Goodall

Penn virologist Beatrice Hahn recalls her research partnership with Jane Goodall and their work to uncover the origins of HIV.

2 min. read

Is housework holding back wage equality?

Is housework holding back wage equality?

New research from Wharton associate professor of business economics and public policy Corinne Low links unequal domestic workloads to stalled progress on closing the wage gap—and even declining marriage rates.

From Knowledge at Wharton

2 min. read

Mechanisms of a rare, serious skin disease point to new targeted treatments

Mechanisms of a rare, serious skin disease point to new targeted treatments

A team of dermatologists and researchers at the Perelman School of Medicine has found a way to directly target neutrophils, a type of immune cell implicated in Sweet’s syndrome, with the potential for treating the disease without steroids.

Women’s labor and political agency in Delhi
Four women street vendors sell shoes and footwear on a Delhi street.

Four women street vendors sell shoes and footwear on a Delhi street.

(Image: Kannagi Khanna)

Women’s labor and political agency in Delhi

Rashi Sabherwal, a doctoral student in political science, explores how women engage politically in society in informal roles through her research in India.

2 min. read