A look back at 2024 through Penn Today stories nocred A look back at 2024 through Penn Today stories Revisit some of the stories that highlighted the events, breakthroughs, people, and research across the University this year.
Brain tumor organoids accurately model patient response to CAR T cell therapy A patient-derived glioblastoma organoid treated with dual-target CAR-T cells. T cells (magenta) infiltrate the tumor organoid and kill tumor cells (blue; yellow indicates dying cells).(Image: Yusha Sun and Xin Wang from the laboratories of Guo-li Ming and Hongjun Song) Brain tumor organoids accurately model patient response to CAR T cell therapy Lab-grown tumors respond to cell therapy the same as tumors in the patients’ brains, according to researchers at Penn Medicine. 2 min. read
A lipid nanoparticle delivers an mRNA cure for preeclampsia Kelsey Swingle at work in the lab of Michael Mitchell.(Image: Kevin Monko) A lipid nanoparticle delivers an mRNA cure for preeclampsia Doctoral student Kelsey Swingle developed a lipid nanoparticle that delivers an mRNA therapeutic that reduces maternal blood pressure through the end of gestation and improves fetal health and blood circulation in the placenta.
Trust in court system at record low: Gallup Penn In the News The Hill Trust in court system at record low: Gallup An October survey from the Annenberg Public Policy Center found that the public’s trust in the U.S. Supreme Court has dropped to a record low. Family offices face hidden risks in making direct investments Penn In the News CNBC Family offices face hidden risks in making direct investments According to a study by Raphael “Raffi” Amit of the Wharton School and colleagues, direct investments in private companies could mean taking on more risk than expected if family offices aren’t leveraging their resources. For kids with rare genetic disorders, customized CRISPR treatments offer hope Penn In the News NPR For kids with rare genetic disorders, customized CRISPR treatments offer hope Scientists at Penn are trying to develop a template for groups of rare conditions that are similar enough to be affected by a single, easily adaptable gene-editing treatment. In mouse studies, new hope against a dangerous complication of pregnancy Penn In the News HealthDay In mouse studies, new hope against a dangerous complication of pregnancy Doctoral student Kelsey Swingle in the School of Engineering and Applied Science and colleagues are using mRNA molecules to treat pre-eclampsia, a common pregnancy complication. Payroll deduction savings programs improve retirement security: State auto IRAs are vital to expanding coverage Penn In the News AARP.org Payroll deduction savings programs improve retirement security: State auto IRAs are vital to expanding coverage New AARP research based on a methodology published by the Wharton School finds that about half of American working adults lack access to a payroll-deduction workplace retirement savings plan, making it much more difficult to save for retirement. Keto diet metabolite may power up CAR T cells to kill cancer Image: iStock/Naeblys Keto diet metabolite may power up CAR T cells to kill cancer Laboratory studies reveal a potentially low-tech intervention to improve personalized cell therapy. What a new innovation index tells us about Philadelphia Penn In the News Technical.ly Philly What a new innovation index tells us about Philadelphia Penn is lauded for its research and development efforts, including the modified mRNA technique that was commercialized into a COVID vaccine and won its researchers a Nobel Prize last year. Load More
Family offices face hidden risks in making direct investments Penn In the News CNBC Family offices face hidden risks in making direct investments According to a study by Raphael “Raffi” Amit of the Wharton School and colleagues, direct investments in private companies could mean taking on more risk than expected if family offices aren’t leveraging their resources. For kids with rare genetic disorders, customized CRISPR treatments offer hope Penn In the News NPR For kids with rare genetic disorders, customized CRISPR treatments offer hope Scientists at Penn are trying to develop a template for groups of rare conditions that are similar enough to be affected by a single, easily adaptable gene-editing treatment. In mouse studies, new hope against a dangerous complication of pregnancy Penn In the News HealthDay In mouse studies, new hope against a dangerous complication of pregnancy Doctoral student Kelsey Swingle in the School of Engineering and Applied Science and colleagues are using mRNA molecules to treat pre-eclampsia, a common pregnancy complication. Payroll deduction savings programs improve retirement security: State auto IRAs are vital to expanding coverage Penn In the News AARP.org Payroll deduction savings programs improve retirement security: State auto IRAs are vital to expanding coverage New AARP research based on a methodology published by the Wharton School finds that about half of American working adults lack access to a payroll-deduction workplace retirement savings plan, making it much more difficult to save for retirement. Keto diet metabolite may power up CAR T cells to kill cancer Image: iStock/Naeblys Keto diet metabolite may power up CAR T cells to kill cancer Laboratory studies reveal a potentially low-tech intervention to improve personalized cell therapy. What a new innovation index tells us about Philadelphia Penn In the News Technical.ly Philly What a new innovation index tells us about Philadelphia Penn is lauded for its research and development efforts, including the modified mRNA technique that was commercialized into a COVID vaccine and won its researchers a Nobel Prize last year. Load More
For kids with rare genetic disorders, customized CRISPR treatments offer hope Penn In the News NPR For kids with rare genetic disorders, customized CRISPR treatments offer hope Scientists at Penn are trying to develop a template for groups of rare conditions that are similar enough to be affected by a single, easily adaptable gene-editing treatment. In mouse studies, new hope against a dangerous complication of pregnancy Penn In the News HealthDay In mouse studies, new hope against a dangerous complication of pregnancy Doctoral student Kelsey Swingle in the School of Engineering and Applied Science and colleagues are using mRNA molecules to treat pre-eclampsia, a common pregnancy complication. Payroll deduction savings programs improve retirement security: State auto IRAs are vital to expanding coverage Penn In the News AARP.org Payroll deduction savings programs improve retirement security: State auto IRAs are vital to expanding coverage New AARP research based on a methodology published by the Wharton School finds that about half of American working adults lack access to a payroll-deduction workplace retirement savings plan, making it much more difficult to save for retirement. Keto diet metabolite may power up CAR T cells to kill cancer Image: iStock/Naeblys Keto diet metabolite may power up CAR T cells to kill cancer Laboratory studies reveal a potentially low-tech intervention to improve personalized cell therapy. What a new innovation index tells us about Philadelphia Penn In the News Technical.ly Philly What a new innovation index tells us about Philadelphia Penn is lauded for its research and development efforts, including the modified mRNA technique that was commercialized into a COVID vaccine and won its researchers a Nobel Prize last year. Load More
In mouse studies, new hope against a dangerous complication of pregnancy Penn In the News HealthDay In mouse studies, new hope against a dangerous complication of pregnancy Doctoral student Kelsey Swingle in the School of Engineering and Applied Science and colleagues are using mRNA molecules to treat pre-eclampsia, a common pregnancy complication. Payroll deduction savings programs improve retirement security: State auto IRAs are vital to expanding coverage Penn In the News AARP.org Payroll deduction savings programs improve retirement security: State auto IRAs are vital to expanding coverage New AARP research based on a methodology published by the Wharton School finds that about half of American working adults lack access to a payroll-deduction workplace retirement savings plan, making it much more difficult to save for retirement. Keto diet metabolite may power up CAR T cells to kill cancer Image: iStock/Naeblys Keto diet metabolite may power up CAR T cells to kill cancer Laboratory studies reveal a potentially low-tech intervention to improve personalized cell therapy. What a new innovation index tells us about Philadelphia Penn In the News Technical.ly Philly What a new innovation index tells us about Philadelphia Penn is lauded for its research and development efforts, including the modified mRNA technique that was commercialized into a COVID vaccine and won its researchers a Nobel Prize last year. Load More
Payroll deduction savings programs improve retirement security: State auto IRAs are vital to expanding coverage Penn In the News AARP.org Payroll deduction savings programs improve retirement security: State auto IRAs are vital to expanding coverage New AARP research based on a methodology published by the Wharton School finds that about half of American working adults lack access to a payroll-deduction workplace retirement savings plan, making it much more difficult to save for retirement. Keto diet metabolite may power up CAR T cells to kill cancer Image: iStock/Naeblys Keto diet metabolite may power up CAR T cells to kill cancer Laboratory studies reveal a potentially low-tech intervention to improve personalized cell therapy. What a new innovation index tells us about Philadelphia Penn In the News Technical.ly Philly What a new innovation index tells us about Philadelphia Penn is lauded for its research and development efforts, including the modified mRNA technique that was commercialized into a COVID vaccine and won its researchers a Nobel Prize last year. Load More
Keto diet metabolite may power up CAR T cells to kill cancer Image: iStock/Naeblys Keto diet metabolite may power up CAR T cells to kill cancer Laboratory studies reveal a potentially low-tech intervention to improve personalized cell therapy.
What a new innovation index tells us about Philadelphia Penn In the News Technical.ly Philly What a new innovation index tells us about Philadelphia Penn is lauded for its research and development efforts, including the modified mRNA technique that was commercialized into a COVID vaccine and won its researchers a Nobel Prize last year.